Evidence map›Paper›PMID 37248514›Full record

GuidelineMilitary Medical Research2023

Management of regional citrate anticoagulation for continuous renal replacement therapy: guideline recommendations from Chinese emergency medical doctor consensus.

Shu-Yuan Liu, Sheng-Yong Xu, Lu Yin, Ting Yang, Kui Jin, Qiu-Bin Zhang, Feng Sun, Ding-Yu Tan, Tian-Yu Xin, Yu-Guo Chen and 4 more

Abstract readPractice Guideline
In one paragraph

Guideline in Military Medical Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shu-Yuan Liu *Emergency Department, The Sixth Medical Center, Chinese PLA General Hospital, Beijing, 100048, China.
Sheng-Yong Xu *State Key Laboratory of Complex Severe and Rare Diseases, Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China.
Lu Yin *Emergency Department, Peking University Shenzhen Hospital, Shenzhen, 518000, China.
Ting YangEmergency Department, The First Affiliated Hospital of Kunming Medical University, Kunming, 650000, China.
Kui JinEmergency Department, The First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, China.
Qiu-Bin ZhangEmergency Department, The Second Affiliated Hospital of Hainan Medical College, Haikou, 570100, China.
Feng SunEmergency Department, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Ding-Yu TanEmergency Department, Northern Jiangsu People's Hospital, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China.
Tian-Yu XinEmergency Department, The Sixth Medical Center, Chinese PLA General Hospital, Beijing, 100048, China.
Yu-Guo ChenEmergency Department and Chest Pain Center, Qilu Hospital of Shandong University, Jinan, 100005, China. chen919085@sdu.edu.cn.
Xiao-Dong ZhaoEmergency Department, The Fourth Medical Center, Chinese PLA General Hospital, Beijing, 100048, China. zxd63715@126.com.
Xue-Zhong YuState Key Laboratory of Complex Severe and Rare Diseases, Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China. yxz@pumch.cn.
Jun XuState Key Laboratory of Complex Severe and Rare Diseases, Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China. xujunfree@126.com.ORCID 0000-0001-5014-4238
Emergency Medical Doctor Branch of the Chinese Medical Doctor Association

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous renal replacement therapy (CRRT) is widely used for treating critically-ill patients in the emergency department in China. Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation during CRRT. Regional citrate anticoagulation (RCA) has been shown to potentially be safer and more effective and is now recommended as the preferred anticoagulant method for CRRT. However, there is still a lack of unified standards for RCA management in the world, and there are many problems in using this method in clinical practice. The Emergency Medical Doctor Branch of the Chinese Medical Doctor Association (CMDA) organized a panel of domestic emergency medicine experts and international experts of CRRT to discuss RCA-related issues, including the advantages and disadvantages of RCA in CRRT anticoagulation, the principle of RCA, parameter settings for RCA, monitoring of RCA (mainly metabolic acid-base disorders), and special issues during RCA. Based on the latest available research evidence as well as the paneled experts' clinical experience, considering the generalizability, suitability, and potential resource utilization, while also balancing clinical advantages and disadvantages, a total of 16 guideline recommendations were formed from the experts' consensus.

Indexed as

CitratesContinuous Renal Replacement TherapyAnticoagulantsChinaConsensusHumansAnticoagulantsCitratesAnticoagulationCitrateContinuous renal replacement therapyEmergencyExpert consensusGuideline

Identifiers

PMID37248514
PMCPMC10226261

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.