Evidence map›Paper›PMID 37250135›Full record

ArticleFrontiers in physiology2023

Canonical Wnt signaling is not required for

Ghazi-Abdullah Saroya, Erica Siismets, Max Hu, Christopher Panaretos, Adam Rice, Kurt Reynolds, Chengji J Zhou, Vesa Kaartinen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ghazi-Abdullah SaroyaDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, United States.
Erica SiismetsDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, United States.
Max HuDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, United States.
Christopher PanaretosDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, United States.
Adam RiceDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, United States.
Kurt ReynoldsSchool of Medicine, Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children-Northern California, University of California at Davis, Sacramento, CA, United States.
Chengji J ZhouSchool of Medicine, Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children-Northern California, University of California at Davis, Sacramento, CA, United States.
Vesa KaartinenDepartment of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, United States.
University of Michigan · USUniversity of California, Davis · US

Funding

Tissue Engineering and RegenerationT32DE007057 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID H. KOHN · 1985 to 2026
$17.3M
Cellular and molecular mechanisms of orofacial cleftsR01DE026737 · NIDCR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZHOU, CHENGJI · 2017 to 2021
$3.1M
Surface ectodermal mechanism and maternal intervention of neural tube defectsR01NS102261 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZHOU, CHENGJI · 2018 to 2022
$2.5M
NIDCR NIH HHS R01 DE026737NIDCR NIH HHS T32 DE007057NINDS NIH HHS R01 NS102261
6 · The paper itself

Abstract

The secondary palate forms from two lateral primordia called the palatal shelves which form a contact in the midline, become adherent at the fusing interface (medial edge epithelia, MEE) and subsequently fuse. The gene encoding transforming growth factor-ß3 (

Indexed as

beta-Catenincanonical Wnt signal pathwaycleft palate (CP)palatogenesisTGF-beta3

Identifiers

PMID37250135
PMCPMC10213314
OpenAlexW4378745640

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.