Evidence map›Paper›PMID 37251909›Full record

ReviewHeliyon2023

MicroRNA-372 acts as a double-edged sword in human cancers.

Fatemeh Tajik, Fatemeh Alian, Mohammad Yousefi, Ali Azadfallah, Aref Hoseini, Forogh Mohammadi, Maryam Karimi-Dehkordi, Shahin Alizadeh-Fanalou

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Impact of Mir196a-2 Genotypes on Colorectal Cancer Risk in Taiwan.International journal of molecular sciences · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Fatemeh TajikOncopathology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Fatemeh AlianInstitute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Mohammad YousefiDepartment of Medicine, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Ali AzadfallahDepartment of Medicine, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Aref HoseiniStudent Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Forogh MohammadiDepartment of Veterinary, Agriculture Faculty, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran.
Maryam Karimi-DehkordiDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
Shahin Alizadeh-FanalouDepartment of Clinical Biochemistry, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Semnan University of Medical Sciences · IRIran University of Medical Sciences · IRIslamic Azad University of Kermanshah · IRIslamic Azad University of Shahrekord · IRMazandaran University of Medical Sciences · IRUniversity of Tehran · IRUrmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs or miRs) are non-coding, single-stranded, endogenous RNAs that regulate various biological processes, most notably the pathophysiology of many human malignancies. It process is accomplished by binding to 3'-UTR mRNAs and controlling gene expression at the post-transcriptional level. As an oncogene, miRNAs can either accelerate cancer progression or slow it down as a tumor suppressor. MicroRNA-372 (miR-372) has been found to have an abnormal expression in numerous human malignancies, implying that the miRNA plays a role in carcinogenesis. It is both increased and downregulated in various cancers, and it serves as both a tumor suppressor and an oncogene. This study examines the functions of miR-372 as well as the LncRNA/CircRNA-miRNA-mRNA signaling pathways in various malignancies and analyses its potential prognostic, diagnostic, and therapeutic implications.

Indexed as

CancerFunctionImportanceMicroRNA-372OncogeneTumor suppressor

Identifiers

PMID37251909
PMCPMC10208947
OpenAlexW4378745249

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.