Evidence map›Paper›PMID 37255490›Full record

ArticleInfection and immunity2023

TargeTron Inactivation of Chlamydia trachomatis

Addison G DeBoer, Lei Lei, Chunfu Yang, Craig A Martens, Sarah L Anzick, Sophia Antonioli-Schmit, Robert J Suchland, Grant McClarty, Harlan D Caldwell, Daniel D Rockey

Abstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Journal of bacteriology · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Requirement of GrgA forbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Addison G DeBoerLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Lei LeiLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Chunfu YangLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Craig A MartensNational Institute of Allergy and Infectious Disease, Rocky Mountain Laboratory, Hamilton, Montana, USA.
Sarah L AnzickNational Institute of Allergy and Infectious Disease, Rocky Mountain Laboratory, Hamilton, Montana, USA.
Sophia Antonioli-SchmitNational Institute of Allergy and Infectious Disease, Rocky Mountain Laboratory, Hamilton, Montana, USA.
Robert J SuchlandDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington.
Grant McClartyDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba Winnipeg, Winnipeg, Manitoba, Canada.
Harlan D CaldwellLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-2018-8106
Daniel D RockeyDepartment of Biomedical Sciences, Oregon State University, Corvallis, Oregon, USA.ORCID 0000-0003-0663-9916

Funding

Infectious Diseases Research Technologies Core - RMLZICAI001052 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$133.3M
Functional genomics for ChlamydiaR01AI126785 · NIAID · UNIVERSITY OF WASHINGTON · PI HEFTY, P SCOTT, HYBISKE, KEVIN · 2016 to 2025
$7.1M
Genome-wide analysis of lateral gene transfer in Chlamydia trachomatisR21AI144865 · NIAID · OREGON STATE UNIVERSITY · PI ROCKEY, DANIEL D · 2020 to 2021
$428k
Remnant diagnostic samples for high resolution genotyping of Chlamydia trachomatisR03AI156514 · NIAID · OREGON STATE UNIVERSITY · PI ROCKEY, DANIEL D · 2021 to 2022
$149k
NIAID NIH HHS R01 AI126785NIAID NIH HHS R03 AI156514NIAID NIH HHS R21 AI144865
6 · The paper itself

Abstract

All members of the family Chlamydiaceae have lipopolysaccharides (LPS) that possess a shared carbohydrate trisaccharide antigen, 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) that is functionally uncharacterized. A single gene, genus-specific epitope (

Indexed as

Chlamydia trachomatisLipopolysaccharidesAntibodies, MonoclonalCarbohydrate SequenceEpitopesSugar Acids2-keto-3-deoxyoctonateAntibodies, MonoclonalEpitopesLipopolysaccharidesSugar AcidsChlamydialipopolysaccharidemutantTargeTron

Identifiers

PMID37255490
PMCPMC10353364

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.