Evidence map›Paper›PMID 37256658›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2023

An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of

Katja Koeppen, Thomas H Hampton, Roxanna Barnaby, Carolyn Roche, Scott A Gerber, Young Ah Goo, Byoung-Kyu Cho, Danielle M Vermilyea, Deborah A Hogan, Bruce A Stanton

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Outer membrane vesicles secreted byInfection and immunity · 2026
    Article
  3. Article
  4. Article
  5. Mesenchymal stromal cell extracellular vesicles reduceAmerican journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  6. Let-7b-5p loaded Mesenchymal Stromal Cell Extracellular Vesicles reducebioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Extracellular vesicles secreted by primary human bronchial epithelial cells reduceAmerican journal of physiology. Lung cellular and molecular physiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Katja KoeppenDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.ORCID 0000-0003-1094-0621
Thomas H HamptonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.ORCID 0000-0003-0543-402X
Roxanna BarnabyDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.
Carolyn RocheDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.
Scott A GerberNorris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States.
Young Ah GooMass Spectrometry Technology Access Center, McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States.
Byoung-Kyu ChoMass Spectrometry Technology Access Center, McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States.
Danielle M VermilyeaDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.
Deborah A HoganDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.ORCID 0000-0002-6366-2971
Bruce A StantonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.
Dartmouth College · USJames S. McDonnell Foundation · US

Funding

Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 2018 to 2026
$13.9M
Retrieval, Reprocessing, Normalization and Sharing of Gene Expression and Lung Microbiome Data Sets to Facilitate AI/ML Analysis Studies of Bacterial Lung InfectionsR01HL151385 · NHLBI · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2021 to 2024
$2.4M
Defining human kinase-substrate networks and their dynamic regulationR01GM122846 · NIGMS · DARTMOUTH COLLEGE · PI GERBER, SCOTT A. · 2017 to 2020
$1.5M
NHLBI NIH HHS R01 HL151385NIDDK NIH HHS P30 DK117469NIGMS NIH HHS R01 GM122846
6 · The paper itself

Abstract

Lung infections caused by antibiotic-resistant strains of

Indexed as

Extracellular VesiclesPseudomonas InfectionsAnti-Bacterial AgentsCiprofloxacinFluoroquinolonesHumansPseudomonas aeruginosaRNA, RibosomalAnti-Bacterial AgentsCiprofloxacinFluoroquinolonesRNA, Ribosomalantibiotic resistanceciprofloxacinEVshost-pathogen interactionPseudomonas

Identifiers

PMID37256658
PMCPMC10390050
OpenAlexW4378783662

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.