ORAI Calcium Channels: Regulation, Function, Pharmacology, and Therapeutic Targets.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

27 citing papers in PubMed.

1. Anti-resorptive and anabolic therapies improve Falls Risk Assessment Score (FRAS) in postmenopausal women with type 2 diabetes mellitus.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
   Trial
2. TH1177, Clemastine, and Benzhydryl Derivatives Act as Novel Extracellular Blockers of ORAI Channels.Biomolecules · 2026
   Article
3. Slick K+ channels contribute to cardiac remodeling, fibrosis, and dysfunction in postinfarction hearts.JCI insight · 2026
   Article
4. Spent Coffee Ground Extracts: A Sustainable Source of Antioxidant and Immunomodulatory Bioactives for Managing Lifestyle-Related Chronic Diseases.International journal of molecular sciences · 2026
   Review
5. STIM/Orai-Mediated Store-Operated CaCells · 2026
   Review
6. Latrophilin-1-Mediated GCells · 2026
   Article
7. Ion channels and GPCRs as pharmacological regulators of ferroptosis and pyroptosis in metabolic diseases.Diabetology & metabolic syndrome · 2026
   Review
8. Heart Failure: Epidemiology, Pathophysiology, and Management.MedComm · 2026
   Review
9. TRPC Channels as Mediators of Hypoxia-Induced Pulmonary Hypertension in Obstructive Sleep Apnea.International journal of molecular sciences · 2026
   Review
10. Calcium signaling in psoriasis: from pathogenesis to therapeutic opportunities.Frontiers in immunology · 2026
    Review
11. A rare ORAI1 missense variant associates with risk of vascular diseases in White British adults.PloS one · 2026
    Article
12. TMCO1 as an Endoplasmic Reticulum Calcium Load-Activated Channel: Mechanisms and Disease Implications.Biomolecules · 2025
    Review
13. Functional characterization of the store-operated calcium entry pathway in naked mole-rat cells.Open biology · 2025
    Article
14. Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy.MedComm · 2025
    Review
15. Novel Compounds Target Aberrant Calcium Signaling in the Treatment of Relapsed High-Risk Neuroblastoma.International journal of molecular sciences · 2025
    Article
16. α-Latrotoxin Actions in the Absence of Extracellular CaToxins · 2025
    Article
17. Metal Ion Signaling in Biomedicine.Chemical reviews · 2025
    Review
18. The Molecular Biology of Placental Transport of Calcium to the Human Foetus.International journal of molecular sciences · 2025
    Review
19. Effects of aging on calcium channels in skeletal muscle.Frontiers in molecular biosciences · 2025
    Review
20. Mast cell-neuron axis as a core mechanism in chronic pruritus of atopic dermatitis: from mechanistic insights to therapeutic targets.Frontiers in immunology · 2025
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as