Evidence map›Paper›PMID 37267740›Full record

ArticleDiagnostic microbiology and infectious disease2023

Qualitative detection of enterovirus D68 from PrimeStore® molecular transport medium: implications for home- and self-collection.

Hai Nguyen-Tran, Samantha Reno, Eric Mwangi, Marta Mentel, Randy Hengartner, Samuel R Dominguez, Kevin Messacar, Sarah A Jung

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hai Nguyen-TranDepartment of Pediatrics, Section of Infectious Diseases, University of Colorado School of Medicine, Aurora, CO, USA.
Samantha RenoDepartment of Pathology and Laboratory Medicine, Children's Hospital Colorado, Aurora, CO, USA.
Eric MwangiDepartment of Pathology and Laboratory Medicine, Children's Hospital Colorado, Aurora, CO, USA.
Marta MentelDepartment of Pathology and Laboratory Medicine, Children's Hospital Colorado, Aurora, CO, USA.
Randy HengartnerDepartment of Pathology and Laboratory Medicine, Children's Hospital Colorado, Aurora, CO, USA.
Samuel R DominguezDepartment of Pediatrics, Section of Infectious Diseases, University of Colorado School of Medicine, Aurora, CO, USA; Department of Pathology and Laboratory Medicine, Children's Hospital Colorado, Aurora, CO, USA.
Kevin MessacarDepartment of Pediatrics, Section of Infectious Diseases, University of Colorado School of Medicine, Aurora, CO, USA.
Sarah A JungDepartment of Pathology and Laboratory Medicine, Children's Hospital Colorado, Aurora, CO, USA. Electronic address: Sarah.Jung@childrenscolorado.org.
Children's Hospital Colorado · USUniversity of Colorado Denver · US

Funding

Implementation and Effectiveness of a Rapid Cerebrospinal Fluid Diagnostics Program for Children with Suspected Central Nervous System InfectionK23AI128069 · NIAID · UNIVERSITY OF COLORADO DENVER · PI MESSACAR, KEVIN BRETT · 2017 to 2021
$878k
NIAID NIH HHS K23 AI128069
6 · The paper itself

Abstract

To ensure proper specimen handling for detecting pathogens, like Enterovirus D68 (EV-D68), from home- and self-collection, alternative techniques are needed to ensure safe transport and reliable testing. PrimeStore® Molecular Transport Medium (MTM) may be an option since it does not require cold storage and inactivates virus while preserving RNA for detection. The purpose of this validation study was to demonstrate the ability to detect EV-D68 via rRT-PCR in MTM. Using a quantified EV-D68 positive control standard, MTM limit of detection for EV-D68 RNA is 10

Indexed as

Enterovirus D, HumanEnterovirus InfectionsRespiratory Tract InfectionsDisease OutbreaksHumansPolymerase Chain ReactionEnterovirus D68Home-collectionSelf-collectionTransport mediumValidation

Identifiers

PMID37267740
PMCPMC10330550
OpenAlexW4376865773

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.