Evidence map›Paper›PMID 37270713›Full record

ArticleJournal of bone and mineral metabolism2023

Low-intensity pulsed ultrasound enhances the positive effects of high-intensity treadmill exercise on bone in rats.

Liang Tang, Hao Guo, Keyi Wang, Yaling Zhou, Tianpei Wu, Xiushan Fan, Jianzhong Guo, Lijun Sun, Dean Ta

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of bone and mineral metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Liang Tang *Institute of Sports Biology, Shaanxi Normal University, Xi'an, 710119, China.
Hao Guo *Institute of Sports Biology, Shaanxi Normal University, Xi'an, 710119, China.
Keyi WangInstitute of Sports Biology, Shaanxi Normal University, Xi'an, 710119, China.
Yaling ZhouInstitute of Sports Biology, Shaanxi Normal University, Xi'an, 710119, China.
Tianpei WuInstitute of Sports Biology, Shaanxi Normal University, Xi'an, 710119, China.
Xiushan FanInstitute of Sports Biology, Shaanxi Normal University, Xi'an, 710119, China.
Jianzhong GuoShaanxi Key Laboratory of Ultrasonics, Shaanxi Normal University, Xi'an, 710119, China.
Lijun SunInstitute of Sports Biology, Shaanxi Normal University, Xi'an, 710119, China. sunlijun@snnu.edu.cn.
Dean TaDepartment of Electronic Engineering, Fudan University, Shanghai, 200433, China. tda@fudan.edu.cn.
Shaanxi Normal University · CNFudan University · CN

Funding

Fundamental Research Funds for the Central Universities GK202103123National Natural Science Foundation of China 11774213National Natural Science Foundation of China 11974233National Natural Science Foundation of China 12034005Young Scholar Cultivation Project of Physical Education College of Shaanxi Normal University 2022BA003Young Scholar Cultivation Project of Physical Education College of Shaanxi Normal University 2022BA004
6 · The paper itself

Abstract

introductionModerate exercise benefits bone health, but excessive loading leads to bone fatigue and a decline in mechanical properties. Low-intensity pulsed ultrasound (LIPUS) can stimulate bone formation. The purpose of this study was to explore whether LIPUS could augment the skeletal benefits of high-intensity exercise. MATERIALS AND

methodsMC3T3-E1 osteoblasts were treated with LIPUS at 80 mW/cm

resultsLIPUS significantly accelerated the proliferation, differentiation, mineralization, and migration of MC3T3-E1 cells. Compared to 30 mW/cm

conclusionLIPUS could augment the skeletal benefits of high-intensity exercise through Wnt/β-catenin signal pathway.

Indexed as

beta CateninUltrasonic WavesAnimalsCell DifferentiationMusclesRatsWnt Signaling Pathwaybeta CateninAngiogenesisBone microstructureHigh-intensity treadmill exerciseLIPUSMechanical properties

Identifiers

PMID37270713
OpenAlexW4379278534

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.