ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023
An All-In-One Transient Theranostic Platform for Intelligent Management of Hemorrhage.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- An Injectable, Self-Expanding Hemostatic Foam for Field-Compatible Postpartum Hemorrhage Management.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Natural Polymer-Based Hemostatic Hydrogels with Advanced Material and Structural Designs for Functional Applications.Pharmaceutics · 2026Review
- Hemostatic Tough Adhesives seal tissue and control hemorrhage.Nature communications · 2026Article
- From nature to plate: harnessing naturally abundant scaffolds for sustainable production of protein-inspired cultivated snack.NPJ science of food · 2025Article
- Biocompatible Mesoporous Materials for Bone Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- An Ultra-Robust, Highly Compressible Silk/Silver Nanowire Sponge-Based Wearable Pressure Sensor for Health Monitoring.Biosensors · 2025Article
- Smart design in biopolymer-based hemostatic sponges: From hemostasis to multiple functions.Bioactive materials · 2025Review
- A self-elastic chitosan sponge integrating active and passive hemostatic mechanisms for effectively managing uncontrolled coagulopathic hemorrhage.Materials today. Bio · 2024Article
- Nanobioactive Blood-Derived Shear-Thinning Biomaterial for Tissue Engineering Applications.Applied materials today · 2024Article
- Recent advancements in implantable neural links based on organic synaptic transistors.Exploration (Beijing, China) · 2024Review
- Highly Electroconductive Metal-Polymer Hybrid Foams Based on Silver Nanowires: Manufacturing and Characterization.Polymers · 2024Article
- An All-In-One Transient Theranostic Platform for Intelligent Management of Hemorrhage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- A microporous liraglutide-releasing silk fibroin scaffold improves islet transplantation outcomes through anti-inflammatory effect.Cell transplantationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 5 institutions in 3 countries.
Funding
Abstract
Developing theranostic devices to detect bleeding and effectively control hemorrhage in the prehospital setting is an unmet medical need. Herein, an all-in-one theranostic platform is presented, which is constructed by sandwiching silk fibroin (SF) between two silver nanowire (AgNW) based conductive electrodes to non-enzymatically diagnose local bleeding and stop the hemorrhage at the wound site. Taking advantage of the hemostatic property of natural SF, the device is composed of a shape-memory SF sponge, facilitating blood clotting, with ≈82% reduction in hemostatic time in vitro as compared with untreated blood. Furthermore, this sandwiched platform serves as a capacitive sensor that can detect bleeding and differentiate between blood and other body fluids (i.e., serum and water) via capacitance change. In addition, the AgNW electrode endows anti-infection efficiency against Escherichia coli and Staphylococcus aureus. Also, the device shows excellent biocompatibility and gradually biodegrades in vivo with no major local or systemic inflammatory responses. More importantly, the theranostic platform presents considerable hemostatic efficacy comparable with a commercial hemostat, Dengen, in rat liver bleeding models. The theranostic platform provides an unexplored strategy for the intelligent management of hemorrhage, with the potential to significantly improve patients' well-being through the integration of diagnostic and therapeutic capabilities.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.