Evidence map›Paper›PMID 37271984›Full record

ReviewThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2024

Daniela M Roth, Jeremie Oliver Piña, Melissa MacPherson, Curtis Budden, Daniel Graf

Open access · greenAbstract readReview
In one paragraph

Review in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Daniela M RothSchool of Dentistry, University of Alberta, Edmonton, Canada.ORCID 0000-0001-8156-4681
Jeremie Oliver PiñaEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.
Melissa MacPhersonDepartment of Medical Genetics, University of Alberta, Edmonton, Canada.ORCID 0000-0002-3382-7480
Curtis BuddenDepartment of Surgery, University of Alberta, Edmonton, Canada.
Daniel GrafSchool of Dentistry, University of Alberta, Edmonton, Canada.ORCID 0000-0003-1163-8117
University of Alberta · CAEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cranial sutures are complex structures integrating mechanical forces with osteogenesis which are often affected in craniofacial syndromes. While premature fusion is frequently described, rare pathological widening of cranial sutures is a comparatively understudied phenomenon. This narrative review aims to bring to light the biologically variable underlying causes of widened sutures and persistent fontanelles leading to a common outcome. The authors herein present four syndromes, selected from a literature review, and their identified biological mechanisms in the context of altered suture physiology, exploring the roles of progenitor cell differentiation, extracellular matrix production, mineralization, and bone resorption. This article illustrates the gaps in understanding of complex craniofacial disorders, and the potential for further unification of genetics, cellular biology, and clinical pillars of health science research to improve treatment outcomes for patients.

Indexed as

Cranial SuturesCraniosynostosesHumanscranial suturescraniofacial developmentgeneticspathophysiology

Identifiers

PMID37271984
PMCPMC11468227
OpenAlexW4379376036

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.