Evidence map›Paper›PMID 37273652›Full record

SynthesisFrontiers in aging neuroscience2023

Systematic review of

Steven Jett, Camila Boneu, Camila Zarate, Caroline Carlton, Vibha Kodancha, Matilde Nerattini, Michael Battista, Silky Pahlajani, Schantel Williams, Jonathan P Dyke and 1 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Lipid droplets and major metabolic disorders.Molecular biology reports · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Targeting mitophagy in neurodegenerative diseases.Nature reviews. Drug discovery · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. A Quantitative Comparison ofSensors (Basel, Switzerland) · 2024
    Article
  15. Article
  16. Article
  17. 3D ultra-short echo timeResearch square · 2024
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Steven JettDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Camila BoneuDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Camila ZarateDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Caroline CarltonDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Vibha KodanchaDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Matilde NerattiniDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Michael BattistaDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Silky PahlajaniDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Schantel WilliamsDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Jonathan P DykeDepartment of Radiology, Weill Cornell Medical College, New York, NY, United States.
Lisa MosconiDepartment of Neurology, Weill Cornell Medical College, New York, NY, United States.
Cornell University · US

Funding

Timing of Menopausal Hormone Therapy across Perimenopause to Menopause Transition: Neuroimmune System in BrainP01AG026572 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adam C. Raikes · 2006 to 2026
$53.7M
PEROXYNITRITE, CELL SIGNALING AND APOPTOSISF32AG005793 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SPEAR, NATHAN H · 1997 to 1997
–
NIA NIH HHS F32 AG005793NIA NIH HHS P01 AG026572
6 · The paper itself

Abstract

Many lines of evidence suggest that mitochondria have a central role in aging-related neurodegenerative diseases, such as Alzheimer's disease (AD). Mitochondrial dysfunction, cerebral energy dysmetabolism and oxidative damage increase with age, and are early event in AD pathophysiology and may precede amyloid beta (Aβ) plaques.

Indexed as

agingAlzheimer's diseaseAPOEbrain metabolic imagingdementiaphosphorous-31 magnetic resonance spectroscopysex differencesystematic review

Identifiers

PMID37273652
PMCPMC10232902
OpenAlexW4377023756

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.