Evidence map›Paper›PMID 37275232›Full record

ArticleFrontiers in physiology2023

Biological sex differences in renin angiotensin system enzymes ACE and ACE2 regulate normal tissue response to radiation injury.

Guru Prasad Sharma, Anne Frei, Brian Fish, Tracy Gasperetti, Dana Veley, Nathan Szalewski, Austen Nissen, Heather A Himburg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Radiomitigators: Breakthroughs in Post-Radiation Recovery.Antioxidants (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Activation of Angiotensin-Converting Enzyme 2 Mitigates Gastrointestinal Acute Radiation Syndrome.International journal of radiation oncology, biology, physics · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Sex differences in radiation research.International journal of radiation biology · 2024
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Guru Prasad SharmaDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Anne FreiDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Brian FishDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Tracy GasperettiDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Dana VeleyDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Nathan SzalewskiDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Austen NissenDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Heather A HimburgDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Medical College of Wisconsin · US

Funding

Sample Engineering CoreU19AI067773 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRENNER, DAVID JONATHAN · 2005 to 2024
$105.4M
Mechanism of radiation induced endovascular injury and mitigation via the Notch-Dll4 pathwayU01AI133594 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI HIMBURG, HEATHER A · 2018 to 2022
$3.0M
NIAID NIH HHS U01 AI133594NIAID NIH HHS U19 AI067773
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ACEACE2biological sexGI-ARSmedical countermeasuresmyeloid cellsradiation pneumonitisrenin angiotensin system

Identifiers

PMID37275232
PMCPMC10235526
OpenAlexW4377139565

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.