Evidence mapPaperPMID 37277608Full record

ReviewNature reviews. Cardiology2023

Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging: a Consensus Statement from the Quantitative Cardiovascular Imaging Study Group.

Aldo J Vázquez Mézquita, Federico Biavati, Volkmar Falk, Hatem Alkadhi, Reza Hajhosseiny, Pál Maurovich-Horvat, Robert Manka, Sebastian Kozerke, Matthias Stuber, Thorsten Derlin and 18 more

Registry-linked trialOpen access · bronzeAbstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06136806 (Diagnostic Performance of a Novel Ferumoxytol-Enhanced Coronary Magnetic Resonance Angiography/ Venography on Panvascular Disease), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06136806 unknown statusnot on this mapstarted 2024, after this paper: background citation

Diagnostic Performance of a Novel Ferumoxytol-Enhanced Coronary Magnetic Resonance Angiography/ Venography on Panvascular Disease: a Single-center Clinical Study.

Typeobservational_patient_registrySponsorThe First Affiliated Hospital with Nanjing Medical UniversityRan2024 to 2025Enrolled200ConditionsPanvascular DiseaseArmsFerumoxytol Enhanced Magnetic Resonance Angiography( FE-MRA);Coronary/Renal /Lower artery Arteriography, Ferumoxytol Enhanced Magnetic Resonance Venography( FE-MRV), Computed Tomography Pulmonary Angiography, Ultrasound for Lower Extremity Deep Vein.
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 19 institutions in 8 countries.

Aldo J Vázquez Mézquita *Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0001-9641-3587
Federico Biavati *Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Volkmar FalkDepartment of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC), Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-7911-8620
Hatem AlkadhiDiagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-2581-2166
Reza HajhosseinySchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Pál Maurovich-HorvatDepartment of Radiology, Medical Imaging Center, Semmelweis University, Budapest, Hungary.
Robert MankaDiagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Sebastian KozerkeInstitute for Biomedical Engineering, ETH Zurich, University of Zurich, Zurich, Switzerland.
Matthias StuberDepartment of Radiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Thorsten DerlinDepartment of Nuclear Medicine, Hannover Medical School, Hannover, Germany.ORCID http://orcid.org/0000-0002-8786-4105
Keith M ChannonRadcliffe Department of Medicine, University of Oxford and Oxford University Hospitals, Oxford, UK.
Ivana IšgumDepartment of Biomedical Engineering and Physics, Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.ORCID http://orcid.org/0000-0003-1869-5034
Adriaan CoenenDepartment of Radiology, Erasmus University, Rotterdam, Netherlands.
Bernhard FoellmerDepartment of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-1377-3371
Damini DeyDepartments of Biomedical Sciences and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-2236-6970
Rick H J A VollebergDepartment of Cardiology, Radboud University Medical Center, Nijmegen, Netherlands.ORCID http://orcid.org/0000-0001-7471-1006
Felix G MeinelDepartment of Radiology, University Medical Centre Rostock, Rostock, Germany.
Marc R DweckCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Jan J PiekDepartment of Clinical and Experimental Cardiology and Cardiovascular Sciences, Amsterdam UMC, Heart Center, University of Amsterdam, Amsterdam, Netherlands.ORCID http://orcid.org/0000-0001-8666-7129
Tim van de HoefDepartment of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.ORCID http://orcid.org/0000-0003-0682-0619
Ulf LandmesserDZHK (German Centre for Cardiovascular Research) Partner Site, Berlin, Germany.ORCID http://orcid.org/0000-0002-0214-3203
Giulio GuagliumiDivision of Cardiology, IRCCS Galeazzi Sant'Ambrogio Hospital, Milan, Italy.
Andreas A GiannopoulosDepartment of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
René M BotnarSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.ORCID http://orcid.org/0000-0002-9447-4367
Ramzi KhamisNational Heart and Lung Institute, Imperial College London, London, UK.
Michelle C WilliamsCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
David E NewbyCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Marc DeweyDepartment of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany. dewey@charite.de.ORCID http://orcid.org/0000-0002-4402-2733
University of Zurich · CHCharité - Universitätsmedizin Berlin · DEUniversity of Edinburgh · GBAmsterdam University Medical Centers · NLDeutsches Herzzentrum der Charité · DECedars-Sinai Medical Center · USErasmus University Rotterdam · NLETH Zurich · CHImperial College London · GBIstituto Clinico Sant'Ambrogio · ITKing's College London · GBMedizinische Hochschule Hannover · DEPontificia Universidad Católica de Chile · CLRadboud University Nijmegen · NLSemmelweis University · HUUniversity Hospital of Lausanne · CHUniversity Medical Center Utrecht · NLUniversity of Oxford · GBUniversity of Rostock · DE

Funding

British Heart Foundation CH/09/002/26360British Heart Foundation CH/16/1/32013British Heart Foundation FS/17/16/32560British Heart Foundation FS/ICRF/20/26002British Heart Foundation SP/17/16/33519
6 · The paper itself

Abstract

The detection and characterization of coronary artery stenosis and atherosclerosis using imaging tools are key for clinical decision-making in patients with known or suspected coronary artery disease. In this regard, imaging-based quantification can be improved by choosing the most appropriate imaging modality for diagnosis, treatment and procedural planning. In this Consensus Statement, we provide clinical consensus recommendations on the optimal use of different imaging techniques in various patient populations and describe the advances in imaging technology. Clinical consensus recommendations on the appropriateness of each imaging technique for direct coronary artery visualization were derived through a three-step, real-time Delphi process that took place before, during and after the Second International Quantitative Cardiovascular Imaging Meeting in September 2022. According to the Delphi survey answers, CT is the method of choice to rule out obstructive stenosis in patients with an intermediate pre-test probability of coronary artery disease and enables quantitative assessment of coronary plaque with respect to dimensions, composition, location and related risk of future cardiovascular events, whereas MRI facilitates the visualization of coronary plaque and can be used in experienced centres as a radiation-free, second-line option for non-invasive coronary angiography. PET has the greatest potential for quantifying inflammation in coronary plaque but SPECT currently has a limited role in clinical coronary artery stenosis and atherosclerosis imaging. Invasive coronary angiography is the reference standard for stenosis assessment but cannot characterize coronary plaques. Finally, intravascular ultrasonography and optical coherence tomography are the most important invasive imaging modalities for the identification of plaques at high risk of rupture. The recommendations made in this Consensus Statement will help clinicians to choose the most appropriate imaging modality on the basis of the specific clinical scenario, individual patient characteristics and the availability of each imaging modality.

Indexed as

AtherosclerosisCoronary Artery DiseaseCoronary StenosisPlaque, AtheroscleroticConstriction, PathologicCoronary AngiographyHumans

Identifiers

PMID37277608
OpenAlexW4379388985

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.