Evidence mapPaperPMID 37280646Full record

ReviewChinese medicine2023

Formation of a traditional Chinese medicine self-assembly nanostrategy and its application in cancer: a promising treatment.

Ju Huang, Yu Zhu, Hang Xiao, Jingwen Liu, Songtao Li, Qiao Zheng, Jianyuan Tang, Xiangrui Meng

Abstract readReview
In one paragraph

Review in Chinese medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Characterization andCurrent drug delivery · 2025
    Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ju Huang *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China.ORCID http://orcid.org/0000-0002-6898-7687
Yu Zhu *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China.
Hang Xiao *Capital Medical University, Beijing, People's Republic of China.
Jingwen LiuHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China.
Songtao LiHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China.
Qiao ZhengHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China.
Jianyuan TangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China. tangjy@cdutcm.edu.cn.
Xiangrui MengHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China. jonias@126.com.

Funding

National Natural Science Foundation of China 82204778Science and Technology Department of Sichuan Province 2022YFG0145Science and Technology Development Fund of Macao Special Administrative Region (SKL-QRCM[UM]
6 · The paper itself

Abstract

Traditional Chinese medicine (TCM) has been used for centuries to prevent and treat a variety of illnesses, and its popularity is increasing worldwide. However, the clinical applications of natural active components in TCM are hindered by the poor solubility and low bioavailability of these compounds. To address these issues, Chinese medicine self-assembly nanostrategy (CSAN) is being developed. Many active components of TCM possess self-assembly properties, allowing them to form nanoparticles (NPs) through various noncovalent forces. Self-assembled NPs (SANs) are also present in TCM decoctions, and they are closely linked to the therapeutic effects of these remedies. SAN is gaining popularity in the nano research field due to its simplicity, eco-friendliness, and enhanced biodegradability and biocompatibility compared to traditional nano preparation methods. The self-assembly of active ingredients from TCM that exhibit antitumour effects or are combined with other antitumour drugs has generated considerable interest in the field of cancer therapeutics. This paper provides a review of the principles and forms of CSAN, as well as an overview of recent reports on TCM that can be used for self-assembly. Additionally, the application of CSAN in various cancer diseases is summarized, and finally, a concluding summary and thoughts are proposed. We strongly believe that CSAN has the potential to offer fresh strategies and perspectives for the modernization of TCM.

Indexed as

ApplicationCancerCombined chemotherapyFormationSelf-assembly nanostrategyTraditional Chinese medicine

Identifiers

PMID37280646
PMCPMC10243050

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.