ArticleEnvironmental health perspectives2023
Associations of Gestational Perfluoroalkyl Substances Exposure with Early Childhood BMI
Article in Environmental health perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Maternal perfluoroalkyl and polyfluoroalkyl substances (PFAS) exposure and preeclampsia: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Metabolomic data presents challenges for epidemiological meta-analysis: a case study of childhood body mass index from the ECHO consortium.Metabolomics : Official journal of the Metabolomic Society · 2024Pooled it
- Joint Associations of Prenatal Per- and Polyfluoroalkyl Substances and Metal Mixtures with Adiposity in Childhood and Adolescence.Environmental science & technology · 2026Article
- Sociodemographic predictors of PFAS exposure among a combined sample of U.S. pregnant women: an Environmental influences on Child Health Outcomes (ECHO) public-use dataset analysis.Journal of exposure science & environmental epidemiology · 2026Article
- Per- and Polyfluoroalkyl Substance Exposure Associated with Later Puberty in Norwegian Girls: Data from the Bergen Growth Study 2.Environment & health (Washington, D.C.) · 2026Article
- Prenatal PFAS exposure and offspring health: evidence review and implications for intergenerational risk assessment.Frontiers in public health · 2026Review
- Association between prenatal exposures to per- and polyfluoroalkyl substances and early language development in the ECHO cohort.Neurotoxicology · 2025Article
- Plastic Pollution and Child Health: A Narrative Review of Micro- and Nanoplastics, Additives, and Developmental Risks.Journal of clinical medicine · 2025Review
- Prenatal PFAS exposure and outcomes related to maternal gut microbiome composition in later pregnancy.Environmental research · 2025Article
- Prenatal PFAS exposures and cardiometabolic health in middle childhood in the MIREC cohort.Environmental research · 2025Article
- Age-specific associations between per- and polyfluoroalkyl substances exposure and metabolic syndrome: a cross-sectional study.Lipids in health and disease · 2025Article
- Development and child health in a world of synthetic chemicals.Pediatric research · 2025Review
- Impact of PFOS Exposure on Murine Fetal Hematopoietic Stem Cells, Associated with Intrauterine Metabolic Perturbation.Environmental science & technology · 2025Article
- Gestational and Early Childhood Exposure to Barium and Cardiometabolic Risk in Preschoolers: Findings From the Ma'anshan Birth Cohort Study in China.Journal of the American Heart Association · 2025Article
- Review
- Exposome Burden Scores to Summarize Environmental Chemical Mixtures: Creating a Fair and Common Scale for Cross-study Harmonization, Report-back and Precision Environmental Health.Current environmental health reports · 2025Review
- Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants.Nature communications · 2025Article
- Associations of early life per- and polyfluoroalkyl substances (PFAS) exposure with body mass index and risk of overweight or obesity at age 2-18 years: Mixture analysis in the prospective Boston Birth Cohort.Environment international · 2025Article
- The Built Environment and Childhood Obesity.Pediatric clinics of North America · 2024Review
- Exposure to Per- and Polyfluoroalkyl Substances and Timing of Puberty in Norwegian Boys: Data from the Bergen Growth Study 2.Environmental science & technology · 2024Article
Corrections and comments
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Authors and funding
19 authors at 13 institutions in 1 country.
Funding
Abstract
backgroundGestational per- and polyfluoroalkyl substances (PFAS) exposure may be associated with adiposity and increased risk of obesity among children and adolescents. However, results from epidemiological studies evaluating these associations are inconsistent.
objectivesWe estimated the associations of pregnancy PFAS concentrations with child body mass index (BMI)
methodsWe used data from 1,391 mother-child pairs who enrolled in eight Environmental influences on Child Health Outcomes (ECHO) cohorts (enrolled: 1999-2019). We quantified concentrations of seven PFAS in maternal plasma or serum in pregnancy. We measured child weight and height between the ages of 2 and 5 y and calculated age- and sex-specific BMI
resultsWe observed a pattern of subtle positive associations of PFAS concentrations in pregnancy with BMI DISCUSSION: In eight U.S.-based prospective cohorts, gestational exposure to higher levels of PFAS were associated with slightly higher childhood BMI
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.