Evidence map›Paper›PMID 37295067›Full record

ReviewCurrent opinion in cell biology2023

The (social) lives, deaths, and biophysical phases of lipid droplets.

W Mike Henne

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Physiological Responses in the Hepatopancreas ofAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Heterogeneity, dynamics and organelle interactions of lipid droplets.Nature reviews. Molecular cell biology · 2026
    Review
  4. Review
  5. Article
  6. Lipid droplets and cellular lipid flux.Nature cell biology · 2024
    Review
  7. Spartin-mediated lipid transfer facilitates lipid droplet turnover.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Spartin-mediated lipid transfer facilitates lipid droplet turnover.bioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

W Mike HenneDepartment of Cell Biology, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: mike.henne@utsouthwestern.edu.

Funding

UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeffrey M Zigman · 2022 to 2026
$7.4M
Spatial determinants in lipid metabolic organization at the sub-organelle levelR35GM119768 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Mike Henne · 2016 to 2026
$4.1M
Mechanisms of lipid droplet organization and functional diversificationR01DK126887 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Mike Henne, sarah huen · 2021 to 2026
$2.4M
NIDDK NIH HHS P30 DK127984NIDDK NIH HHS R01 DK126887NIGMS NIH HHS R35 GM119768
6 · The paper itself

Abstract

Lipid droplets (LDs) are major lipid storage organelles, sequestering energy-rich triglycerides and serving as nutrient sinks for cellular homeostasis. Observed for over a century but generally ignored, LDs are now appreciated to play key roles in organismal physiology and disease. They also form numerous functional contacts with other organelles. Here, we highlight recent studies examining LDs from distinct perspectives of their life cycle: their biogenesis, "social" life as they interact with other organelles, and deaths via lipolysis or lipophagy. We also discuss recent work showing how changes in LD lipid content alter the biophysical phases of LD lipids, and how this may fine-tune the LD protein landscape and ultimately LD function.

Indexed as

Lipid DropletsLipolysisLipid MetabolismProteinsTriglyceridesProteinsTriglycerides

Identifiers

PMID37295067
PMCPMC10782554

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.