Evidence mapPaperPMID 37297993Full record

ReviewJournal of clinical medicine2023

MINOCA Associated with a Myocardial Bridge: Pathogenesis, Diagnosis and Treatment.

Riccardo Rinaldi, Giuseppe Princi, Giulia La Vecchia, Alice Bonanni, Giovanni Alfonso Chiariello, Alessandro Candreva, Felice Gragnano, Paolo Calabrò, Filippo Crea, Rocco A Montone

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Riccardo RinaldiDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, 00168 Rome, Italy.ORCID 0000-0003-0559-2626
Giuseppe PrinciDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Giulia La VecchiaDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Alice BonanniDepartment of Cardiovascular Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-8382-255X
Giovanni Alfonso ChiarielloDepartment of Cardiovascular Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Alessandro CandrevaDepartment of Cardiology, Zurich University Hospital, 8091 Zurich, Switzerland.ORCID 0000-0002-6676-7541
Felice GragnanoDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 80133 Naples, Italy.ORCID 0000-0002-6943-278X
Paolo CalabròDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 80133 Naples, Italy.ORCID 0000-0002-5018-830X
Filippo CreaDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Rocco A MontoneDepartment of Cardiovascular Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-6439-1018
Università Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity Hospital of Zurich · CH

Funding

Grant of the Italian Ministry of Health - Ricerca Finalizzata Giovani Ricercatori GR2019-1237019
6 · The paper itself

Abstract

Myocardial bridging (MB) is the most frequent congenital coronary anomaly characterized by a segment of an epicardial coronary artery that passes through the myocardium. MB is an important cause of myocardial ischemia and is also emerging as a possible cause of myocardial infarction with non-obstructed coronary arteries (MINOCA). There are multiple mechanisms underlying MINOCA in patients with MB (i.e., MB-mediated increased risk of epicardial or microvascular coronary spasm, atherosclerotic plaque disruption and spontaneous coronary artery dissection). The identification of the exact pathogenetic mechanism is crucial in order to establish a patient-tailored therapy. This review provides the most up-to-date evidence regarding the pathophysiology of MINOCA in patients with MB. Moreover, it focuses on the available diagnostic tools that could be implemented at the time of coronary angiography to achieve a pathophysiologic diagnosis. Finally, it focuses on the therapeutic implications associated with the different pathogenetic mechanisms of MINOCA in patients with MB.

Indexed as

diagnosismanagementMINOCAmyocardial bridgepathogenesis

Identifiers

PMID37297993
PMCPMC10253711
OpenAlexW4379057671

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.