Evidence map›Paper›PMID 37298165›Full record

ArticleInternational journal of molecular sciences2023

Insights on the Hypoglycemic Potential of

Luisa Bellachioma, Camilla Morresi, Alfonso Albacete, Purificación A Martínez-Melgarejo, Gianna Ferretti, Giorgia Giorgini, Roberta Galeazzi, Elisabetta Damiani, Tiziana Bacchetti

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07261475 (Acute Effects of Water Extract of Crocus Sativus Tepals on Metabolic Health Parameters in Patients With Obesity and Prediabetes), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07261475 early_phase1recruitingnot on this mapstarted 2026, after this paper: background citation

Acute Effects of Water Extract of Crocus Sativus Tepals on Metabolic Health Parameters in Patients With Obesity and Prediabetes

TypeinterventionalSponsorUniversity of PrimorskaRan2026 to 2026Enrolled20ConditionsPrediabetes, Obesity & OverweightArmsCrocus sativus tepals cold aqueous extract, cold water
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Luisa BellachiomaDepartment of Life and Environmental Sciences, Marche Polytechnic University, Via Brecce Bianche, 60131 Ancona, Italy.
Camilla MorresiDepartment of Life and Environmental Sciences, Marche Polytechnic University, Via Brecce Bianche, 60131 Ancona, Italy.
Alfonso AlbaceteCentro de Edafología y Biología Aplicada del Segura, Agencia Estatal Consejo Superior de Investigaciones Científicas (CEBAS-CSIC), Department of Plant Nutrition, Campus Universitario de Espinardo, E-30100 Murcia, Spain.ORCID 0000-0003-1332-8593
Purificación A Martínez-MelgarejoCentro de Edafología y Biología Aplicada del Segura, Agencia Estatal Consejo Superior de Investigaciones Científicas (CEBAS-CSIC), Department of Plant Nutrition, Campus Universitario de Espinardo, E-30100 Murcia, Spain.
Gianna FerrettiDepartment of Clinical Science and Odontostomatology, Marche Polytechnic University, Via Brecce Bianche, 60131 Ancona, Italy.
Giorgia GiorginiDepartment of Life and Environmental Sciences, Marche Polytechnic University, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0002-4198-1787
Roberta GaleazziDepartment of Life and Environmental Sciences, Marche Polytechnic University, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0003-1792-654X
Elisabetta DamianiDepartment of Life and Environmental Sciences, Marche Polytechnic University, Via Brecce Bianche, 60131 Ancona, Italy.
Tiziana BacchettiDepartment of Life and Environmental Sciences, Marche Polytechnic University, Via Brecce Bianche, 60131 Ancona, Italy.
Marche Polytechnic University · ITConsejo Superior de Investigaciones Científicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-prandial hyperglycemia typical of diabetes mellitus could be alleviated using plant-derived compounds such as polyphenols, which could influence the activities of enzymes involved in carbohydrate digestion and of intestinal glucose transporters. Here, we report on the potential anti-hyperglycemic effect of

Indexed as

CrocusDiabetes MellitusCaco-2 CellsGlucoseHumansHypoglycemic AgentsMolecular Docking SimulationPancreatic alpha-AmylasesPlant ExtractsPolyphenolsGlucoseHypoglycemic AgentsPancreatic alpha-AmylasesPlant ExtractsPolyphenolscircular economyCrocus sativusdiabetesintestinal glucose absorptionpolyphenolspost-prandial glycemia

Identifiers

PMID37298165
PMCPMC10252962
OpenAlexW4378228142

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.