ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2023
Utility of the Kidney Failure Risk Equation and Estimated GFR for Estimating Time to Kidney Failure in Advanced CKD.
Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Saudi Clinical Practice Guidelines for management of diabetic kidney disease in adults.Saudi medical journal · 2025Guideline
- Representation of multimorbidity and frailty in the development and validation of kidney failure prognostic prediction models: a systematic review.BMC medicine · 2024Pooled it
- Optimal patient care in advanced chronic kidney disease progressing to kidney failure.Nature reviews. Nephrology · 2026Review
- Timely AVF creation in late-referral hemodialysis patients, a two-cohort study: Too late to plan, not too late to act.The journal of vascular access · 2026Article
- Dynamic Risk Prediction of Graft Failure after Deceased Donor Kidney Transplant.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Plasma proteomics based on machine learning predict the early risk of kidney outcomes in patients with DKD: a prospective cohort study from UK Biobank.Frontiers in nephrology · 2026Article
- ECG-based deep learning for chronic kidney disease detection and cardiovascular risk prediction.BMC medical informatics and decision making · 2025Article
- Artificial intelligence and pediatric acute kidney injury: a mini-review and white paper.Frontiers in nephrology · 2025Review
- Clinical impact of the Kidney Failure Risk Equation for vascular access planning.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- Enhancing vascular access planning in CKD: validating the 40% KFRE threshold for predicting ESKD in a French retrospective cohort study.Clinical kidney journal · 2024Article
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9 authors at 3 institutions in 1 country.
Funding
Abstract
RATIONALE &
objectiveThe Kidney Failure Risk Equation (KFRE) predicts the 2-year risk of kidney failure for patients with chronic kidney disease (CKD). Translating KFRE-predicted risk or estimated glomerular filtration rate (eGFR) into time to kidney failure could inform decision making for patients approaching kidney failure. STUDY
designRetrospective cohort. SETTING &
participantsCKD Outcomes and Practice Patterns Study (CKDOPPS) cohort of patients with an eGFR<60mL/min/1.73m EXPOSURE: 2-year KFRE risk or eGFR. OUTCOME: Kidney failure defined as initiation of dialysis or kidney transplantation. ANALYTICAL APPROACH: Accelerated failure time (Weibull) models used to estimate the median, 25th, and 75th percentile times to kidney failure starting from KFRE values of 20%, 40%, and 50%, and from eGFR values of 20, 15, and 10mL/min/1.73m
resultsOverall, 1,641 participants were included (mean age 69±13 years; median eGFR of 28mL/min/1.73m LIMITATIONS: Inability to account for competing risks when estimating time to kidney failure.
conclusionsAmong those with eGFR<15mL/min/1.73m PLAIN-LANGUAGE SUMMARY: Clinicians often talk to patients with advanced chronic kidney disease about the level of kidney function expressed as the estimated glomerular filtration rate (eGFR) and about the risk of developing kidney failure, which can be estimated using the Kidney Failure Risk Equation (KFRE). In a cohort of patients with advanced chronic kidney disease, we examined how eGFR and KFRE risk predictions corresponded to the time patients had until reaching kidney failure. Among those with eGFR<15mL/min/1.73m
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