Evidence map›Paper›PMID 37310442›Full record

ArticleInternational orthopaedics2023

Application of diffuse optical back reflection spectroscopy for determining articular cartilage thickness in a clinical setting.

Yiğit Ali Üncü, Özlem Özbey Ünlü, Birce Gümüş, Serkan Uslu, Çağrı Turgut, Yetkin Söyüncü, Uğur Bilge, İsmail Üstünel, Murat Canpolat

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Article in International orthopaedics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yiğit Ali ÜncüBiomedical Optics Research Unit, Department of Biophysics, School of Medicine, Akdeniz University, Room F1-18, Konyaaltı, Antalya, 07070, Turkey.
Özlem Özbey ÜnlüDepartment of Histology and Embryology, School of Medicine, Akdeniz University, Antalya, Turkey.
Birce GümüşBiomedical Optics Research Unit, Department of Biophysics, School of Medicine, Akdeniz University, Room F1-18, Konyaaltı, Antalya, 07070, Turkey.
Serkan UsluBiomedical Optics Research Unit, Department of Biophysics, School of Medicine, Akdeniz University, Room F1-18, Konyaaltı, Antalya, 07070, Turkey.
Çağrı TurgutDepartment of Orthopedics and Traumatology, Antalya Training and Research Hospital, University of Health Science, Antalya, Turkey.
Yetkin SöyüncüDepartment of Orthopedics and Traumatology, School of Medicine, Akdeniz University, Antalya, Turkey.
Uğur BilgeDepartment of Biostatistics and Medical Informatics, School of Medicine, Akdeniz University, Antalya, Turkey.
İsmail ÜstünelDepartment of Histology and Embryology, School of Medicine, Akdeniz University, Antalya, Turkey.
Murat CanpolatBiomedical Optics Research Unit, Department of Biophysics, School of Medicine, Akdeniz University, Room F1-18, Konyaaltı, Antalya, 07070, Turkey. canpolat@akdeniz.edu.tr.ORCID http://orcid.org/0000-0003-3298-9725
Akdeniz University · TRAntalya Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDevelop a spectroscopic method to assess cartilage thickness during the arthroscopic examination.

methodsCurrently, arthroscopy assesses cartilage damage visually; outcomes are based on the surgeon's subjective experience. Light reflection spectroscopy is a promising method for measuring cartilage thickness based on the absorption of light by the subchondral bone. In the presented study, in vivo diffuse optical back reflection spectroscopic measurements were acquired by gently placing an optical fibre probe on different locations of the articular cartilage of 50 patients during complete knee replacement surgery. The optical fibre probe consists of two optical fibers with a diameter of 1 mm to deliver the light and detect back-reflected light from the cartilage. Centre to centre distance between the source and the detector fibers was 2.4 mm. Actual thicknesses of the articular cartilage samples were measured under microscopy using histopathological staining.

resultsUsing half of the samples in the patient data, a linear regression model was formed to estimate cartilage thicknesses from the spectroscopic measurements. The regression model was then used to predict the cartilage thickness in the second half of the data. The cartilage thickness was predicted with a mean error of 8.7% if the actual thickness was less than 2.5 mm (R

conclusionThe outer diameter of the optical fibre probe was 3 mm, which can fit into the arthroscopy channel and can be used to measure the cartilage thickness in real-time during the arthroscopic examination of the articular cartilage.

Indexed as

Arthroplasty, Replacement, KneeCartilage, ArticularArthroscopyHumansLinear ModelsSpectrum AnalysisCartilage thicknessHistological measurementsIn vivoSpectroscopic measurementsVIS–NIR spectroscopy

Identifiers

PMID37310442
OpenAlexW4380423038

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.