Evidence map›Paper›PMID 37314021›Full record

ArticleBJPsych open2023

Cognitive impairment in adults under compulsory psychiatric care: association with psychotic symptoms and high-dose antipsychotics.

Maria Karanikola, Maria Nystazaki, Katerina Kaikoushi, Nicos Middleton, Andreas Chatzittofis

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Maria KaranikolaDepartment of Nursing, School of Health Sciences, Cyprus University of Technology, Cyprus.ORCID https://orcid.org/0000-0003-2708-1851
Maria NystazakiDepartment of Nursing, School of Health Sciences, Cyprus University of Technology, Cyprus.ORCID https://orcid.org/0000-0002-1357-2230
Katerina KaikoushiDepartment of Nursing, School of Health Sciences, Cyprus University of Technology, Cyprus; and Cyprus Mental Health Services, Cyprus.ORCID https://orcid.org/0000-0002-4927-3072
Nicos MiddletonDepartment of Nursing, School of Health Sciences, Cyprus University of Technology, Cyprus.
Andreas ChatzittofisUniversity of Cyprus Medical School, University of Cyprus, Cyprus; and Department of Clinical Sciences, Umeå University, Sweden.ORCID https://orcid.org/0000-0002-6635-9564
Cyprus University of Technology · CYUniversity of Cyprus · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited evidence on the association between cognitive function, psychotic symptoms and doses of antipsychotics in adults under compulsory psychiatric care.

aimsWe assessed (a) the degree of cognitive impairment in adults involuntarily hospitalised for compulsory psychiatric care and (b) correlation of Montreal Cognitive Assessment (MoCA) score with psychotic symptoms, polypharmacy and prescription of high-dose antipsychotics.

methodThis was a nationwide, cross-sectional study, conducted at the only referral state hospital for compulsory psychiatric care in Cyprus (December 2016-February 2018). Τhe MoCA was applied for the assessment of cognitive functioning. The Positive and Negative Syndrome Scale (PANSS) was applied for the assessment of psychotic symptoms.

resultsThe sample comprised 187 men and 116 women. The mean MoCA score was 22.09 (reported scale range (RSR): 3-30); the mean PANSS general symptoms subscale score was 49.60 (RSR = 41-162). The participants who reported positive psychiatric history (mean 21.71, s.d. 5.37), non-adherence to pharmacotherapy (mean 21.32, s.d. 5.56) and prescription of high-dose antipsychotics (with medication prescribed as needed: mean 21.31, s.d. 5.70; without medication prescribed as needed: mean 20.71, s.d. 5.78) had lower mean MoCA scores compared with those who reported negative psychiatric history (mean 23.42, s.d. 4.51;

conclusionsOur findings support the evaluation of cognitive functioning in adults under compulsory psychiatric care via the MoCA tool, with focus on those prescribed high-dose antipsychotics, with positive mental health history and non-adherence to pharmacotherapy.

Indexed as

Cognitive impairmentinvoluntary hospital admissionMontreal Cognitive Assessmentpolypharmacypsychotic disorder

Identifiers

PMID37314021
PMCPMC10305086
OpenAlexW4380576261

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.