Evidence mapPaperPMID 37314571Full record

Observational studyWorld journal of urology2023

Association between hysterectomy and kidney stone disease: results from the National Health and Nutrition Examination Survey 2007-2018 and Mendelian randomization analysis.

Ye Yuan, Wei Tan, Yinchao Huang, Hao Huang, Yadong Li, Yuanqing Gou, Shengjie Zeng, Zili Hu

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ye YuanDepartment of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.ORCID http://orcid.org/0000-0002-4575-2324
Wei TanDepartment of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Yinchao HuangDepartment of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Hao HuangDepartment of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Yadong LiDepartment of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Yuanqing GouDepartment of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Shengjie ZengDepartment of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Zili HuDepartment of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. 300445@hospital.cqmu.edu.cn.ORCID http://orcid.org/0000-0001-6437-5264
Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHysterectomy is one of the most common types of gynecological operations and it is associated with numerous postoperative complications. Few studies have reported a definitive association between hysterectomy and kidney stone disease (KSD). This study aimed to explore whether hysterectomy increases the risk of KSD.

methodsThis is a cross-sectional study that used six continuous cycles of data obtained from the National Health and Nutrition Examination Survey from 2007 to 2018. The correlations between hysterectomy or age at hysterectomy and the prevalence of KSD were assessed using weighted multivariable-adjusted logistic regression. Further, five methods of two-sample Mendelian randomization (MR) were applied to decrease bias and infer causality in the observational study.

resultsAfter adjusting for potential confounders, hysterectomy (OR: 1.37, 95% CI 1.04-1.81) was found to be positively associated with the prevalence of KSD, whereas age at hysterectomy was found to be negatively associated with the prevalence of KSD (OR: 0.96, 95% CI: 0.94-0.98). In the inverse-variance weighted method, MR analyses suggested that genetically predicted hysterectomy is causally associated with a higher risk of KSD (OR: 11.961, 95% CI 1.12-1.28E2).

conclusionsHysterectomy could increase the risk of KSD. Younger age at hysterectomy is associated with a higher risk of KSD. Further prospective cohort studies with larger sample sizes and longer follow-up times are needed.

Indexed as

Kidney CalculiMendelian Randomization AnalysisCross-Sectional StudiesFemaleHumansHysterectomyNutrition SurveysPolymorphism, Single NucleotideProspective StudiesAgeHysterectomyKidney stone diseaseMendelian randomizationNational health and nutrition examination survey

Identifiers

PMID37314571
OpenAlexW4380576216

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.