ArticleAmerican journal of physiology. Endocrinology and metabolism2023
Postabsorptive muscle protein synthesis is higher in outpatients as compared to inpatients.
Paul T Reidy, Michael S Borack, Jared M Dickinson, Chad C Carroll, Nicholas A Burd, Micah J Drummond, Christopher S Fry, Bradley S Lambert, David M Gundermann, Erin L Glynn and 8 more
Open access · greenAbstract read
In one paragraphArticle in American journal of physiology. Endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
18 authors at 3 institutions in 1 country.
Paul T ReidyCenter for Metabolic Health, University of Texas Medical Branch, Galveston, Texas, United States.ORCID 0000-0002-3068-4429 Michael S BorackCenter for Metabolic Health, University of Texas Medical Branch, Galveston, Texas, United States.
Jared M DickinsonCenter for Metabolic Health, University of Texas Medical Branch, Galveston, Texas, United States.
Micah J DrummondDepartment of Physical Therapy & Athletic Training, University of Utah, Salt Lake City, Utah, United States.ORCID 0000-0001-5961-8890 Christopher S FryCenter for Metabolic Health, University of Texas Medical Branch, Galveston, Texas, United States.ORCID 0000-0002-4207-6594 Bradley S LambertCenter for Metabolic Health, University of Texas Medical Branch, Galveston, Texas, United States.
David M GundermannCenter for Metabolic Health, University of Texas Medical Branch, Galveston, Texas, United States.
Erin L GlynnCenter for Metabolic Health, University of Texas Medical Branch, Galveston, Texas, United States.
Melissa M MarkofskiSealy Center on Aging, University of Texas Medical Branch, Galveston, Texas, United States.ORCID 0000-0003-0214-4246 Kyle L TimmermanDepartment of Internal Medicine/Geriatrics, University of Texas Medical Branch, Galveston, Texas, United States.
Tatiana MoroSealy Center on Aging, University of Texas Medical Branch, Galveston, Texas, United States.ORCID 0000-0002-1404-1511 Elena VolpiSealy Center on Aging, University of Texas Medical Branch, Galveston, Texas, United States.
Matthew P HarberHuman Performance Laboratory, Ball State University, Muncie, Indiana, United States.ORCID 0000-0002-6183-1487 Blake B RasmussenCenter for Metabolic Health, University of Texas Medical Branch, Galveston, Texas, United States.ORCID 0000-0001-7854-5375 The University of Texas Medical Branch at Galveston · USBall State University · USUniversity of Utah · US
Funding
UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7MNutritional and Contractile Regulation of Muscle GrowthR01AR049877 · NIAMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI RASMUSSEN, BLAKE B · 2004 to 2012
$3.3MLOOH-induced muscle atrophy with ageR01AG074535 · NIA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Micah J Drummond, Katsuhiko Funai · 2022 to 2026
$3.0MNovel molecular mechanisms of skeletal muscle insulin resistance in physically inactive older adultsR01AG050781 · NIA · UNIVERSITY OF UTAH · PI DRUMMOND, MICAH J · 2016 to 2020
$1.7MAnalgesics and resistance training in older individualsR01AG020532 · NIA · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI TRAPPE, TODD A · 2004 to 2008
$1.4MNIAMS NIH HHS R01 AR049877NIA NIH HHS P30 AG024832NIA NIH HHS R01 AG020532NIA NIH HHS R01 AG050781NIA NIH HHS R01 AG074535
6 · The paper itselfAbstract
Several factors affect muscle protein synthesis (MPS) in the postabsorptive state. Extreme physical inactivity (e.g., bedrest) may reduce basal MPS, whereas walking may augment basal MPS. We hypothesized that outpatients would have a higher postabsorptive MPS than inpatients. To test this hypothesis, we conducted a retrospective analysis. We compared 152 outpatient participants who arrived at the research site the morning of the MPS assessment with 350 Inpatient participants who had an overnight stay in the hospital unit before the MPS assessment the following morning. We used stable isotopic methods and collected vastus lateralis biopsies ∼2 to 3 h apart to assess mixed MPS. MPS was ∼12% higher (
Indexed as
InpatientsMuscle ProteinsHumansOutpatientsProtein BiosynthesisRetrospective StudiesMuscle Proteinsdesigninpatientmuscleoutpatientsteps
Identifiers
PMID37315157
PMCPMC10393319
OpenAlexW4380591013
What Socratic holds
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