Evidence map›Paper›PMID 37316506›Full record

ArticleScientific data2023

Host nasopharyngeal transcriptome dataset of a SARS-CoV-2 positive Italian cohort.

Annamaria Salvati, Carlo Ferravante, Jessica Lamberti, Teresa Rocco, Elena Alexandrova, Ylenia D'Agostino, Maksim Sorokin, Victor Efimov, Anton Buzdin, Oriana Strianese and 5 more

Erratum issuedOpen access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Annamaria Salvati *Molecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy.ORCID http://orcid.org/0000-0002-9601-2975
Carlo Ferravante *Molecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy.
Jessica LambertiLaboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi (Sa), 84081, Italy.
Teresa RoccoMolecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy.
Elena AlexandrovaLaboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi (Sa), 84081, Italy.
Ylenia D'AgostinoMolecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy.
Maksim SorokinMoscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, 141701, Russia.
Victor EfimovMoscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, 141701, Russia.
Anton BuzdinMoscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, 141701, Russia.
Oriana StrianeseGenome Research Center for Health, Campus of Medicine, University of Salerno, Baronissi (Sa), 84081, Italy.
Giovanni NassaMolecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy.ORCID http://orcid.org/0000-0001-7453-1240
Roberta TaralloMolecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy.ORCID http://orcid.org/0000-0001-9668-3632
Alessandro WeiszMolecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy.ORCID http://orcid.org/0000-0003-0455-2083
Francesca RizzoMolecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy. frizzo@unisa.it.ORCID http://orcid.org/0000-0003-1783-5015
Giorgio GiuratoMolecular Pathology and Medical Genomics Program, Division of Oncology, AOU 'S. Giovanni di Dio e Ruggi 14 d'Aragona', Università di Salerno, Salerno, 84131, Italy. ggiurato@unisa.it.ORCID http://orcid.org/0000-0002-0538-8978
University of Salerno · ITMoscow Institute of Physics and Technology · RUOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing COVID-19 pandemic caused by SARS-CoV-2 has affected millions of people worldwide and has significant implications for public health. Host transcriptomics profiling provides comprehensive understanding of how the virus interacts with host cells and how the host responds to the virus. COVID-19 disease alters the host transcriptome, affecting cellular pathways and key molecular functions. To contribute to the global effort to understand the virus's effect on host cell transcriptome, we have generated a dataset from nasopharyngeal swabs of 35 individuals infected with SARS-CoV-2 from the Campania region in Italy during the three outbreaks, with different clinical conditions. This dataset will help to elucidate the complex interactions among genes and can be useful in the development of effective therapeutic pathways.

Indexed as

COVID-19TranscriptomeHumansItalyPandemicsSARS-CoV-2

Identifiers

PMID37316506
PMCPMC10264883
OpenAlexW4380685192

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.