Evidence map›Paper›PMID 37325549›Full record

ArticleNAR cancer2023

The 3D chromatin landscape of rhabdomyosarcoma.

Meng Wang, Prethish Sreenivas, Benjamin D Sunkel, Long Wang, Myron Ignatius, Benjamin Z Stanton

Open access · goldAbstract read
In one paragraph

Article in NAR cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Epigenetic determinants of fusion-driven sarcomas: paradigms and challenges.Frontiers in cell and developmental biology · 2024
    Article
  7. Article
  8. A SNAI2/CTCF Interaction is Required forMolecular and cellular biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meng WangNationwide Children's Hospital, Center for Childhood Cancer, Columbus, OH 43205, USA.ORCID https://orcid.org/0000-0002-3457-5908
Prethish SreenivasGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA.ORCID https://orcid.org/0000-0002-1260-4464
Benjamin D SunkelNationwide Children's Hospital, Center for Childhood Cancer, Columbus, OH 43205, USA.
Long WangGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA.
Myron IgnatiusGreehey Children's Cancer Research Institute, Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA.ORCID https://orcid.org/0000-0001-6639-7707
Benjamin Z StantonNationwide Children's Hospital, Center for Childhood Cancer, Columbus, OH 43205, USA.ORCID https://orcid.org/0000-0002-2613-2955
Nationwide Children's Hospital · USThe University of Texas Health Science Center at San Antonio · US

Funding

A role for notch in self renewal in embryonal rhabdomyosarcomaR00CA175184 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI IGNATIUS, MYRON STEVE · 2017 to 2019
$747k
NCI NIH HHS R00 CA175184
6 · The paper itself

Abstract

Rhabdomyosarcoma (RMS) is a pediatric soft tissue cancer with a lack of precision therapy options for patients. We hypothesized that with a general paucity of known mutations in RMS, chromatin structural driving mechanisms are essential for tumor proliferation. Thus, we carried out high-depth

Identifiers

PMID37325549
PMCPMC10261698
OpenAlexW4380487727

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.