Evidence map›Paper›PMID 37329474›Full record

ArticleAging clinical and experimental research2023

The effect of treatment strategy on long-term follow-up results in patients with nonvalvular atrial fibrillation in Turkey: AFTER-2 subgroup analysis.

Raif Kılıç, Tuncay Güzel, Adem Aktan, Muhammed Demir, Bayram Arslan, Faruk Ertaş

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Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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  8. Vascular Endothelial Dysfunction and Immunothrombosis in the Pathogenesis of Atrial Fibrillation.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Raif KılıçDepartment of Cardiology, Memorial Diyarbakır Hospital, Diyarbakır, Turkey. raifklc@hotmail.com.ORCID http://orcid.org/0000-0002-8338-4948
Tuncay GüzelDepartment of Cardiology, Health Science University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.ORCID http://orcid.org/0000-0001-8470-1928
Adem AktanDepartment of Cardiology, Mardin Training and Research Hospital, Mardin, Turkey.ORCID http://orcid.org/0000-0003-0505-9784
Muhammed DemirDepartment of Cardiology, Dicle University, Faculty of Medicine, Diyarbakır, Turkey.ORCID http://orcid.org/0000-0002-9049-7123
Bayram ArslanDepartment of Cardiology, Ergani State Hospital, Diyarbakır, Turkey.ORCID http://orcid.org/0000-0003-2984-9094
Faruk ErtaşDepartment of Cardiology, Dicle University, Faculty of Medicine, Diyarbakır, Turkey.ORCID http://orcid.org/0000-0003-1860-6513
Dicle University · TRDiyarbakır Askeri Hastanesi · TRErgani Devlet Hastanesi · TRMardin Artuklu University · TRSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe performed a subanalysis of the data from the AFTER-2 registry. In our study, we aimed to compare the long-term follow-up results of nonvalvular atrial fibrillation (NVAF) patients in Turkey according to their treatment strategies.

methodsAll consecutive patients older than 18 years of age who presented to cardiology outpatient clinics, had at least one AF attack and did not have rheumatic mitral valve stenosis or prosthetic heart valve disease were included in our prospective study. The patients were divided into two groups as rhythm control and rate control. Stroke, hospitalization and death rates were compared between the groups.

resultsA total of 2592 patients from 35 centers were included in the study. Of these patients, 628 (24.2%) were in the rhythm control group and 1964 (75.8%) in the rate control group. New-onset ischemic cerebrovascular disease or transient ischemic attack (CVD/TIA) was detected at a lower rate in the rhythm control group (3.2% vs. 6.2% p = 0.004). However, there was no significant difference in one-year and five-year mortality rates (9.6% versus 9.0%, p = 0.682 and 31.8% versus 28.6%, p = 0.116, respectively). Hospitalization were found to be significantly higher in patients with rhythm control group (18% vs. 13%, p = 0.002).

conclusionIt was found that rhythm control strategy is preferred in AF patients in Turkey. We found a lower rate of ischemic CVD/TIA in patients in the rhythm control group. Although no difference was observed in mortality rates, we found a higher rate of hospitalization in the rhythm control group.

Indexed as

Atrial FibrillationIschemic Attack, TransientStrokeFollow-Up StudiesHumansProspective StudiesTreatment OutcomeTurkeyArrhythmiaAtrial fibrillationIschaemic stroke

Identifiers

PMID37329474
OpenAlexW4381053189

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.