Evidence map›Paper›PMID 37330364›Full record

ReviewTrends in endocrinology and metabolism: TEM2023

Epithelial and mesenchymal fate decisions in Wolffian duct development.

McKenna J Crossen, Jillian Wilbourne, Allyssa Fogarty, Fei Zhao

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in endocrinology and metabolism: TEM, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

McKenna J CrossenDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA; Endocrinology and Reproductive Physiology Program, University of Wisconsin-Madison, Madison, WI 53706, USA.
Jillian WilbourneDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.
Allyssa FogartyDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA; Comparative Biomedical Sciences Program, University of Wisconsin-Madison, Madison, WI 53706, USA.
Fei ZhaoDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA; Endocrinology and Reproductive Physiology Program, University of Wisconsin-Madison, Madison, WI 53706, USA; Comparative Biomedical Sciences Program, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: fei.zhao@wisc.edu.
University of Wisconsin–Madison · US

Funding

Mechanisms of androgen-dependent Wolffian duct differentiationR01HD111425 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Fei Zhao · 2023 to 2026
$1.7M
Unexpected roles of the male tract mesenchyme in female reproductive tract formationR00HD096051 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI ZHAO, FEI · 2020 to 2022
$727k
NICHD NIH HHS R00 HD096051NICHD NIH HHS R01 HD111425
6 · The paper itself

Abstract

Wolffian ducts (WDs) are the paired embryonic structures that give rise to internal male reproductive tract organs. WDs are initially formed in both sexes but have sex-specific fates during sexual differentiation. Understanding WD differentiation requires insights into the process of fate decisions of epithelial and mesenchymal cells, which are tightly coordinated by endocrine, paracrine, and autocrine signals. In this review, we discuss current advances in understanding the fate-decision process of WD epithelial and mesenchymal lineages from their initial formation at the embryonic stage to postnatal differentiation. Finally, we discuss aberrant cell differentiation in WD abnormalities and pathologies and identify opportunities for future investigations.

Indexed as

Wolffian DuctsCell DifferentiationFemaleHumansMalecell-fate decisionepididymismale reproductive tractsexual differentiationWolffian duct

Identifiers

PMID37330364
PMCPMC10524679
OpenAlexW4380878165

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.