Evidence map›Paper›PMID 37332610›Full record

ArticleiScience2023

Differential response of C9orf72 transcripts following neuronal depolarization.

Layla T Ghaffari, Davide Trotti, Aaron R Haeusler

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Neuronal activity-dependent gene dysregulation inAmerican journal of physiology. Cell physiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Layla T GhaffariJefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Davide TrottiJefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Aaron R HaeuslerJefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Thomas Jefferson University · US

Funding

Exosome-mediated propagation of disease linked poly-dipeptides in C9orf72-FTD/ALSRF1AG057882 · NIA · THOMAS JEFFERSON UNIVERSITY · PI TROTTI, DAVIDE, YANG, YONGJIE · 2018 to 2018
$3.6M
The pathogenic relationship between neuronal activity and C9orf72-linked neurodegenerationRF1NS114128 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI HAEUSLER, AARON RAYMOND · 2020 to 2021
$2.5M
Modeling C9orf72 neuronal pathogenesis as a function of nucleotide repeat lengthR21NS116761 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI HAEUSLER, AARON RAYMOND · 2020 to 2020
$429k
Development of a mouse model of C9ORF72 ALS/FTD expressing RAN translated peptideR21NS090912 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI TROTTI, DAVIDE · 2014 to 2015
$428k
NIA NIH HHS RF1 AG057882NINDS NIH HHS R21 NS090912NINDS NIH HHS R21 NS116761NINDS NIH HHS RF1 NS114128
6 · The paper itself

Abstract

The (G

Indexed as

Cell biologyMolecular biologyNeuroscience

Identifiers

PMID37332610
PMCPMC10272498
OpenAlexW4378071334

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.