Evidence map›Paper›PMID 37337788›Full record

ArticleBiomaterials science2023

A NanoCurvS platform for quantitative and multiplex analysis of curvature-sensing proteins.

Chih-Hao Lu, Ching-Ting Tsai, Taylor Jones Iv, Vincent Chim, Lasse H Klausen, Wei Zhang, Xiao Li, Zeinab Jahed, Bianxiao Cui

Open access · greenAbstract read
In one paragraph

Article in Biomaterials science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chih-Hao LuDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.ORCID http://orcid.org/0000-0001-5759-4629
Ching-Ting TsaiDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.
Taylor Jones IvDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.
Vincent ChimDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.ORCID http://orcid.org/0000-0001-7260-3933
Lasse H KlausenDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.ORCID http://orcid.org/0000-0003-3004-5958
Wei ZhangDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.
Xiao LiDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.
Zeinab JahedDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.
Bianxiao CuiDepartment of Chemistry, Stanford University, Stanford, CA, USA. zjahed@ucsd.edu.ORCID http://orcid.org/0000-0002-8044-5629
Stanford University · USNeurosciences Institute · US

Funding

Nanoscale probes for sensing molecular functions in live cellsR35GM141598 · NIGMS · STANFORD UNIVERSITY · PI CUI, BIANXIAO · 2021 to 2025
$3.4M
An electrophysiology platform that enables robust, scalable and long-term intracellular recording of cardiomyocytesR01HL165491 · NHLBI · STANFORD UNIVERSITY · PI CUI, BIANXIAO · 2022 to 2025
$2.2M
Label-free Optical Recording of Neuroelectric ActivitiesR01NS121934 · NINDS · STANFORD UNIVERSITY · PI CUI, BIANXIAO, MUELLER, HOLGER · 2021 to 2025
$2.2M
NHLBI NIH HHS R01 HL165491NIGMS NIH HHS R35 GM141598NINDS NIH HHS R01 NS121934
6 · The paper itself

Abstract

The cell membrane is characterized by a rich variety of topographical features such as local protrusions or invaginations. Curvature-sensing proteins, including the Bin/Amphiphysin/Rvs (BAR) or epsin N-terminal homology (ENTH) family proteins, sense the bending sharpness and the positive/negative sign of these topographical features to induce subsequent intracellular signaling. A number of assays have been developed to study curvature-sensing properties of proteins

Indexed as

Signal TransductionCell Membrane

Identifiers

PMID37337788
PMCPMC10809791
OpenAlexW4380878215

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.