Evidence map›Paper›PMID 37337906›Full record

ArticleChemical communications (Cambridge, England)2023

Firefly luciferin methyl ester illuminates the activity of multiple serine hydrolases.

Innus Mohammad, Kate L Liebmann, Stephen C Miller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Innus MohammadDepartment of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA. Stephen.miller@umassmed.edu.ORCID http://orcid.org/0000-0002-4353-5633
Kate L LiebmannDepartment of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA. Stephen.miller@umassmed.edu.
Stephen C MillerDepartment of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, 364 Plantation St., Worcester, MA 01605, USA. Stephen.miller@umassmed.edu.ORCID http://orcid.org/0000-0001-7154-7757

Funding

Enhanced synthetic luciferin substrates for firefly luciferaseR01EB013270 · NIBIB · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MILLER, STEPHEN C. · 2011 to 2020
$2.9M
Illuminating serine hydrolase activityR01DA039961 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MILLER, STEPHEN C. · 2015 to 2018
$1.9M
NIBIB NIH HHS R01 EB013270NIDA NIH HHS R01 DA039961
6 · The paper itself

Abstract

Firefly luciferin methyl ester is hydrolyzed by monoacylglycerol lipase MAGL, amidase FAAH, poorly-characterized hydrolase ABHD11, and hydrolases known for

Indexed as

Firefly LuciferinMonoacylglycerol LipasesAmidohydrolasesEnzyme InhibitorsSerineAmidohydrolasesEnzyme InhibitorsFirefly LuciferinMonoacylglycerol LipasesSerine

Identifiers

PMID37337906
PMCPMC10347678

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.