Evidence map›Paper›PMID 37338344›Full record

ArticleMicrobiology spectrum2023

Glyoxylate Shunt and Pyruvate-to-Acetoin Shift Are Specific Stress Responses Induced by Colistin and Ceragenin CSA-13 in Enterobacter hormaechei ST89.

Suhanya V Prasad, Krzysztof Fiedoruk, Magdalena Zakrzewska, Paul B Savage, Robert Bucki

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Suhanya V PrasadDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, Poland.
Krzysztof FiedorukDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, Poland.
Magdalena ZakrzewskaDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, Poland.
Paul B SavageDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, USA.
Robert BuckiDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, Poland.ORCID 0000-0001-7664-9226
Medical University of Białystok · PLBrigham Young University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceragenins, including CSA-13, are cationic antimicrobials that target the bacterial cell envelope differently than colistin. However, the molecular basis of their action is not fully understood. Here, we examined the genomic and transcriptome responses by Enterobacter hormaechei after prolonged exposure to either CSA-13 or colistin. Resistance of the

Indexed as

Anti-Infective AgentsColistinAcetoinAnti-Bacterial AgentsBacterial ProteinsDrug Resistance, BacterialEnterobacterGlyoxylatesMicrobial Sensitivity TestsPyruvic AcidSteroidsAcetoinAnti-Bacterial AgentsAnti-Infective AgentsBacterial Proteinsceragenin CSA-13ColistinGlyoxylatesPyruvic AcidSteroidsadaptive resistanceCAMPscarbon metabolismcerageninscolistinCSA-13next-generation sequencingRNA-seqstress responsetranscriptional regulation

Identifiers

PMID37338344
PMCPMC10434160
OpenAlexW4381248141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.