Evidence map›Paper›PMID 37338381›Full record

ArticleAntimicrobial agents and chemotherapy2023

Activity of Ivermectin and Its Metabolites against Asexual Blood Stage Plasmodium falciparum and Its Interactions with Antimalarial Drugs.

Achaporn Yipsirimetee, Phornpimon Tipthara, Borimas Hanboonkunupakarn, Rupam Tripura, Dysoley Lek, Krittikorn Kümpornsin, Marcus C S Lee, Jetsumon Sattabongkot, Arjen M Dondorp, Nicholas J White and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Efficacy of ivermectin and its metabolites againstAntimicrobial agents and chemotherapy · 2024
    Article
  3. Microbiology spectrum · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 4 countries.

Achaporn YipsirimeteeDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-5227-3401
Phornpimon TiptharaMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Borimas HanboonkunupakarnDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Rupam TripuraMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Dysoley LekNational Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
Krittikorn KümpornsinWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Marcus C S LeeWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.ORCID 0000-0002-4973-0915
Jetsumon SattabongkotMahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Arjen M DondorpMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Nicholas J WhiteMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Kevin C KobylinskiMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Joel TarningMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.ORCID 0000-0003-4566-4030
Kesinee ChotivanichDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-6533-6811
Mahidol University · THCambodia National Malaria Center · KHScripps Research Institute · USWellcome Sanger Institute · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Ivermectin is an endectocide used widely to treat a variety of internal and external parasites. Field trials of ivermectin mass drug administration for malaria transmission control have demonstrated a reduction of

Indexed as

AntimalarialsArtemisininsMalariaMalaria, FalciparumAnimalsDrug CombinationsDrug ResistanceHumansIvermectinPlasmodium falciparumAntimalarialsartemisininArtemisininsDrug CombinationsIvermectinantimalarial drugsdrug-drug interactionsivermectinivermectin metabolitesPlasmodium falciparum

Identifiers

PMID37338381
PMCPMC10368210
OpenAlexW4381248148

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.