Evidence map›Paper›PMID 37340290›Full record

ArticleDoklady. Biochemistry and biophysics2023

Synthesis of 1-[ω-(Bromophenoxy)alkyl]-3-naphthalenylmethyl Derivatives of Uracil and Their Analogues As Probable Inhibitors of Human Cytomegalovirus Replication.

M P Paramonova, E S Gureeva, A A Ozerov, R Snoeck, G Andrei, D A Aleksandrov, A L Khandazhinskaya, M S Novikov, S N Kochetkov

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Article in Doklady. Biochemistry and biophysics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M P ParamonovaVolgograd State Medical University, Volgograd, Russia.
E S GureevaVolgograd State Medical University, Volgograd, Russia.
A A OzerovVolgograd State Medical University, Volgograd, Russia.
R SnoeckRega Institute for Medical Research, KU Leuven, Leuven B-3000, Belgium.
G AndreiRega Institute for Medical Research, KU Leuven, Leuven B-3000, Belgium.
D A AleksandrovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia.
A L KhandazhinskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. khandazhinskaya@bk.ru.
M S NovikovVolgograd State Medical University, Volgograd, Russia.
S N KochetkovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. snk1952@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis of a new series of 1-[ω-(bromophenoxy)alkyl]-uracil derivatives containing in position 3 naphthalen-1-yl-, naphthalen-2-yl-, 1-bromonaphthalen-2-ylmethyl, benzyl, and anthracene 9-methyl fragment was carried out. The antiviral properties of the synthesized compounds were studied against human cytomegalovirus. It was found that the compound that contained a bridge of five methylene groups has a high anti-cytomegalovirus activity in vitro.

Indexed as

CytomegalovirusUracilAntiviral AgentsHumansStructure-Activity RelationshipAntiviral AgentsUracilantiviral activityhuman cytomegalovirussynthesisuracil derivatives

Identifiers

PMID37340290

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.