Evidence map›Paper›PMID 37342616›Full record

ArticleSAGE open medicine2023

Patient preferences of patient selection criteria for upper extremity vascularized composite allotransplantation: A qualitative study.

Karen B Vanterpool, Jessica Gacki-Smith, Max C Downey, Michelle Nordstrom, Michelle Luken, Tiffany Riggleman, Shannon Fichter, Withney Altema, Sally E Jensen, Gregory A Dumanian and 5 more

Abstract read
In one paragraph

Article in SAGE open medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Karen B VanterpoolDepartment of Surgery, NYU Grossman School of Medicine, New York, NY, USA.
Jessica Gacki-SmithCenter for Health Services and Outcomes Research, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Max C DowneyDepartment of Surgery, NYU Grossman School of Medicine, New York, NY, USA.
Michelle NordstromWalter Reed National Military Medical Center, Bethesda, MD, USA.
Michelle LukenWalter Reed National Military Medical Center, Bethesda, MD, USA.
Tiffany RigglemanWalter Reed National Military Medical Center, Bethesda, MD, USA.
Shannon FichterWalter Reed National Military Medical Center, Bethesda, MD, USA.
Withney AltemaWalter Reed National Military Medical Center, Bethesda, MD, USA.
Sally E JensenNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Gregory A DumanianNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Carisa M CooneyDepartment of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Macey L LevanDepartment of Surgery, NYU Grossman School of Medicine, New York, NY, USA.
Scott TintleWalter Reed National Military Medical Center, Bethesda, MD, USA.
Gerald BrandacherDepartment of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Elisa J GordonDepartment of Surgery and Center for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID https://orcid.org/0000-0003-0969-1998

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Upper extremity vascularized composite allotransplantation is a life-enhancing reconstructive treatment option that aims to improve recipients' quality of life and maximize function. This study assessed upper extremity vascularized composite allotransplantation patient selection criteria perceptions among individuals with upper extremity limb loss. The perceptions of individuals with upper extremity limb loss on patient selection criteria may enable vascularized composite allotransplantation centers to improve criteria to avoid mismatched expectations about the posttransplant vascularized composite allotransplantation experience and outcomes. Realistic patient expectations may increase patient adherence, improve outcomes, and reduce vascularized composite allotransplantation graft loss. Methods: We conducted in-depth interviews with civilian and military service members with upper extremity limb loss and upper extremity vascularized composite allotransplantation candidates, participants, and recipients from three US institutions. Interviews assessed perceptions of patient selection criteria for suitability as a candidate for upper extremity vascularized composite allotransplantation. Thematic analysis was used to analyze qualitative data. Results: A total of 50 individuals participated (66% participation rate). Most participants were male (78%), White (72%), with a unilateral limb loss (84%), and a mean age of 45 years. Six themes emerged regarding upper extremity vascularized composite allotransplantation patient selection criteria, including support for candidates who: (1) are of younger age, (2) are in good physical health, (3) have mental stability, (4) are willing to "put in the work," (5) have specific amputation characteristics, and (6) have sufficient social support. Patients had preferences about selecting candidates with unilateral versus bilateral limb loss. Conclusions: Our findings suggest that numerous factors, including medical, social, and psychological characteristics, inform patients' perceptions of patient selection criteria for upper extremity vascularized composite allotransplantation. Patient perceptions of patient selection criteria should inform the development of validated screening measures that optimize patient outcomes.

Indexed as

amputationcandidate evaluationeligibility criteriaethicsHand transplantationinterviewslimb losspatient expectationsperceptionsrehabilitation

Identifiers

PMID37342616
PMCPMC10278401

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.