Evidence map›Paper›PMID 37350911›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2023

Mild Cognitive Impairment: Data-Driven Prediction, Risk Factors, and Workup.

Sajjad Fouladvand, Morteza Noshad, Mary Kane Goldstein, V J Periyakoil, Jonathan H Chen

Open access · greenAbstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sajjad FouladvandStanford Center for Biomedical Informatics Research.
Morteza NoshadStanford Center for Biomedical Informatics Research.
Mary Kane GoldsteinHealth Policy/Center for Primary Care and Outcomes Research.
V J PeriyakoilDepartment of Medicine.
Jonathan H ChenStanford Center for Biomedical Informatics Research.
Center For Policy Research · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over 78 million people will suffer from dementia by 2030, emphasizing the need for early identification of patients with mild cognitive impairment (MCI) at risk, and personalized clinical evaluation steps to diagnose potentially reversible causes. Here, we leverage real-world electronic health records in the observational medical outcomes partnership (OMOP) data model to develop machine learning models to predict MCI up to a year in advance of recorded diagnosis. Our experimental results with logistic regression, random forest, and xgboost models trained and evaluated on more than 531K patient visits show random forest model can predict MCI onset with ROC-AUC of 68.2±0.7. We identify the clinical factors mentioned in clinician notes that are most predictive of MCI. Using similar association mining techniques, we develop a data-driven list of clinical procedures commonly ordered in the workup of MCI cases, that could be used as a basis for guidelines and clinical order set templates.

Identifiers

PMID37350911
PMCPMC10283085
OpenAlexW4381716003

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.