Evidence mapPaperPMID 37351099Full record

ArticleGlobal cardiology science & practice2023

Delayed presentation of biopsy-proven eosinophilic myocarditis following COVID-19 mRNA vaccine.

Chaitra Janga, Tirth Patel, Hussam Al Hennawi, Sarin Atam, Shreeja Shah, Ifrah Naeem, Rahat Memon, Donald C Haas

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Global cardiology science & practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Eosinophilic Myocarditis: A Concise Review.Current cardiology reports · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chaitra JangaDepartment of Internal Medicine, Jefferson Abington Hospital, Abington, PA, USA.
Tirth PatelDepartment of Internal Medicine, Jefferson Abington Hospital, Abington, PA, USA.
Hussam Al HennawiDepartment of Internal Medicine, Jefferson Abington Hospital, Abington, PA, USA.
Sarin AtamDepartment of Internal Medicine, Jefferson Abington Hospital, Abington, PA, USA.
Shreeja ShahDepartment of Internal Medicine, Jefferson Abington Hospital, Abington, PA, USA.
Ifrah NaeemDepartment of Internal Medicine, Jefferson Abington Hospital, Abington, PA, USA.
Rahat MemonDepartment of Internal Medicine, Jefferson Abington Hospital, Abington, PA, USA.
Donald C HaasDepartment of Internal Medicine, Jefferson Abington Hospital, Abington, PA, USA.
Jefferson Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myopericarditis associated with COVID-19 mRNA vaccines has been recognized as an uncommon adverse reaction, especially among young, healthy adult males. Eosinophilic myocarditis is a rare form of inflammation reflecting a hypersensitivity reaction following an inciting event commonly caused by drugs including vaccines. Eosinophilic myocarditis, a subtype of myocarditis, is characterized by eosinophilic myocardial infiltrates. It is usually accompanied by systemic eosinophilia in the form of a drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and is rarely associated with myocyte fibrosis and/or necrosis. In this report, we present a case of biopsy-proven eosinophilic myocarditis in a 24-year-old male patient, likely secondary to COVID-19 mRNA vaccination. To our knowledge, this is the first report to describe delayed eosinophilic myocarditis following the COVID-19 mRNA vaccine. Clinicians should be aware of possible delayed presentation to avoid associated morbidity.

Identifiers

PMID37351099
PMCPMC10282781
OpenAlexW4381081913

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.