Evidence map›Paper›PMID 37354450›Full record

ArticlePhysical therapy2024

The Effect of Different Types of Exercise on Sleep Quality and Architecture in Parkinson Disease: A Single-Blinded Randomized Clinical Trial Protocol.

Jacopo Cristini, Alexandra Potvin-Desrochers, Freddie Seo, Alain Dagher, Ronald B Postuma, Pedro Rosa-Neto, Julie Carrier, Amy W Amara, Simon Steib, Caroline Paquette and 1 more

Open access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Physical therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Jacopo CristiniMemory and Motor Rehabilitation Laboratory (MEMORY-LAB), Jewish Rehabilitation Hospital, Laval, Québec, Canada.
Alexandra Potvin-DesrochersFeil and Oberfeld Research Centre, Jewish Rehabilitation Hospital, Center for Interdisciplinary Research in Rehabilitation (CRIR), Laval, Québec, Canada.
Freddie SeoMemory and Motor Rehabilitation Laboratory (MEMORY-LAB), Jewish Rehabilitation Hospital, Laval, Québec, Canada.
Alain DagherThe Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Québec, Canada.
Ronald B PostumaThe Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Québec, Canada.
Pedro Rosa-NetoThe Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Québec, Canada.
Julie CarrierDépartement de Psychologie, Université de Montréal, Montreal, Québec, Canada.
Amy W AmaraDepartment of Neurology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Simon SteibDepartment of Exercise, Training and Active Aging, Institute of Sport and Sport Science, University of Heidelberg, Heidelberg, Baden-Württemberg, Germany.
Caroline PaquetteFeil and Oberfeld Research Centre, Jewish Rehabilitation Hospital, Center for Interdisciplinary Research in Rehabilitation (CRIR), Laval, Québec, Canada.
Marc RoigMemory and Motor Rehabilitation Laboratory (MEMORY-LAB), Jewish Rehabilitation Hospital, Laval, Québec, Canada.ORCID 0000-0002-1016-467X
Jewish Rehabilitation Hospital · CAMontreal Neurological Institute and Hospital · CAHeidelberg University · DEHôpital du Sacré-Cœur de Montréal · CAUniversity of Colorado Anschutz Medical Campus · US

Funding

CIHR 468982
6 · The paper itself

Abstract

objectivesThe purpose of this trial is to (1) determine the best exercise modality to improve sleep quality and sleep architecture in people with Parkinson disease (PD); (2) investigate whether exercise-induced improvements in sleep mediate enhancements in motor and cognitive function as well as other non-motor symptoms of PD; and (3) explore if changes in systemic inflammation after exercise mediate improvements in sleep.

methodsThis is a multi-site, superiority, single-blinded randomized controlled trial. One hundred fifty persons with PD and sleep problems will be recruited and randomly allocated into 4 intervention arms. Participants will be allocated into 12 weeks of either cardiovascular training, resistance training, multimodal training, or a waiting list control intervention. Assessments will be conducted at baseline, immediately after each intervention, and 8 weeks after each intervention by blinded assessors. Objective sleep quality and sleep architecture will be measured with polysomnography and electroencephalography. Motor and cognitive function will be assessed with the Unified PD Rating Scale and the Scale for Outcomes in PD-Cognition, respectively. Subjective sleep quality, fatigue, psychosocial functioning, and quality of life will be assessed with questionnaires. The concentration of inflammatory biomarkers in blood serum will be assessed with enzyme-linked immunosorbent assays. IMPACT: This study will investigate the effect of different types of exercise on sleep quality and architecture in PD, exploring interactions between changes in sleep quality and architecture with motor and cognitive function and other non-motor symptoms of the disease as well as mechanistic interactions between systemic inflammation and sleep. The results will provide important practical information to guide physical therapists and other rehabilitation professionals in the selection of exercise and the design of more personalized exercise-based treatments aimed at optimizing sleep, motor, and cognitive function in people with PD.

Indexed as

Parkinson DiseaseQuality of LifeExercise TherapyHumansInflammationRandomized Controlled Trials as TopicSleep QualityBrain PlasticityCognitive FunctionExerciseMotor FunctionParkinson DiseaseSleep

Identifiers

PMID37354450
PMCPMC10776310
OpenAlexW4381892188

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.