Evidence map›Paper›PMID 37356607›Full record

ArticleArchives of biochemistry and biophysics2023

3,4-Desaturation of retinoic acid by cytochrome P450 27C1 prevents P450-mediated catabolism.

Sarah M Glass, Yasuhiro Tateishi, F Peter Guengerich, Hong-Jaan Wang

Open access · greenAbstract read
In one paragraph

Article in Archives of biochemistry and biophysics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. The role of the cytochrome P450 superfamily in the skin.Expert reviews in molecular medicine · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Sarah M GlassThe Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232-0146, United States.
Yasuhiro TateishiThe Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232-0146, United States.
F Peter GuengerichThe Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232-0146, United States.
Hong-Jaan WangThe Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232-0146, United States; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan, ROC. Electronic address: hongjaan@mail.ndmctsgh.edu.tw.
Vanderbilt University · US

Funding

Metabolism of Carcinogens and Drugs by Human P450sR01GM118122 · NIGMS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 2016 to 2023
$3.3M
Role and regulation of cytochrome P450 27C1 in human skinF31AR077386 · NIAMS · VANDERBILT UNIVERSITY · PI GLASS, SARAH MARIE · 2020 to 2021
$41k
NIAMS NIH HHS F31 AR077386NIGMS NIH HHS R01 GM118122
6 · The paper itself

Abstract

Cytochrome P450 (P450, CYP) 27C1 is expressed in human skin and catalyzes the 3,4-desaturation of retinoids. The enzyme has a relatively high specificity constant (k

Indexed as

RetinoidsTretinoinCytochrome P-450 Enzyme SystemHumansMicrosomes, LiverReceptors, Retinoic AcidCytochrome P-450 Enzyme SystemReceptors, Retinoic AcidRetinoidsTretinoinCytochrome P450DehydroretinoidsRetinoic acidRetinoid metabolism

Identifiers

PMID37356607
PMCPMC11500474
OpenAlexW4381854924

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.