Evidence mapPaperPMID 37361591Full record

ArticleFrontiers in oncology2023

Pulmonary microbiota signatures adjacent to adenocarcinoma, squamous cell carcinoma and benign lesion.

Jinyou Li, Gang Wu, Ju Yang, Jiai Yan, Dan Li, Qinyue Wang, Yanping Xia, Jie Zhu, Baoliang Guo, Fengyue Cheng and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Jinyou LiDepartment of Thoracic Surgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Gang WuWuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Ju YangDepartment of Nutrition, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Jiai YanDepartment of Nutrition, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Dan LiDepartment of Nutrition, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Qinyue WangDepartment of Nutrition, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Yanping XiaDepartment of Nutrition, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Jie ZhuDepartment of Infection Control, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Baoliang GuoSchool of Bioengineering, Jiangnan University, Wuxi, Jiangsu, China.
Fengyue ChengWuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Jing SunDepartment of Nutrition, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Hong CaoWuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Feng ZhangWuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Jiangnan University · CNChinese Nutrition Society · CNWuxi Fourth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The occurrence and progression of lung cancer are influenced by pulmonary microbiota, yet the relationship between changes in the pulmonary microbiota and lung cancer remains unclear. Methods: To investigate the correlation between pulmonary microbiota and the signature of lung lesions, we analyzed the microbial composition at sites adjacent to the stage 1 adenocarcinoma, squamous carcinoma and benign lesion tissues in 49 patients by using 16S ribosomal RNA gene sequencing. We then conducted Linear discriminant analysis, receiver operating characteristic (ROC) curve analysis and PICRUSt prediction based on 16S sequencing results. Results: Overall, the microbiota composition at sites close to lung lesions showed significant differences between different lesion types. Based on the results of LEfSe analysis, Discussion: The abundance of

Indexed as

adenocarcinomalung cancerpulmonary microbiotaralstoniasquamous cell carcinoma

Identifiers

PMID37361591
PMCPMC10288182
OpenAlexW4380084188

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.