Evidence map›Paper›PMID 37362852›Full record

ReviewJournal of the Indian Institute of Science2023

A Strategic Research Framework for Defeating Diabetes in India: A 21st-Century Agenda.

K M Venkat Narayan, Jithin Sam Varghese, Yara S Beyh, Soura Bhattacharyya, Shweta Khandelwal, Gokul S Krishnan, Karen R Siegel, Tinku Thomas, Anura V Kurpad

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of the Indian Institute of Science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

K M Venkat NarayanHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322 USA.ORCID 0000-0001-8621-5405
Jithin Sam VargheseHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322 USA.
Yara S BeyhLaney Graduate School, Nutrition and Health Sciences Doctoral Program, Emory University, Atlanta, USA.
Soura BhattacharyyaLattice Innovations, New Delhi, India.
Shweta KhandelwalPublic Health Foundation of India, Gurugram, Haryana India.
Gokul S KrishnanRobert Bosch Centre for Data Science and Artificial Intelligence, Indian Institute of Technology Madras, Chennai, India.
Karen R SiegelHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322 USA.
Tinku ThomasDepartment of Biostatistics, St. John's Medical College, Bengaluru, India.
Anura V KurpadDepartment of Physiology, St. John's Medical College, Bengaluru, India.
Emory University · USSt.John's Medical College Hospital · INIndian Institute of Technology Madras · INPublic Health Foundation of India · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indian people are at high risk for type 2 diabetes (T2DM) even at younger ages and lower body weights. Already 74 million people in India have the disease, and the proportion of those with T2DM is increasing across all strata of society. Unique aspects, related to lower insulin secretion or function, and higher hepatic fat deposition, accompanied by the rise in overweight (related to lifestyle changes) may all be responsible for this unrelenting epidemic of T2DM. Yet, research to understand the causes, pathophysiology, phenotypes, prevention, treatment, and healthcare delivery of T2DM in India seriously lags behind. There are major opportunities for scientific discovery and technological innovation, which if tapped can generate solutions for T2DM relevant to the country's context and make leading contributions to global science. We analyze the situation of T2DM in India, and present a four-pillar (etiology, precision medicine, implementation research, and health policy) strategic research framework to tackle the challenge. We offer key research questions for each pillar, and identify infrastructure needs. India offers a fertile environment for shifting the paradigm from imprecise late-stage diabetes treatment toward early-stage precision prevention and care. Investing in and leveraging academic and technological infrastructures, across the disciplines of science, engineering, and medicine, can accelerate progress toward a diabetes-free nation.

Identifiers

PMID37362852
PMCPMC10029804
OpenAlexW4328089093

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.