Evidence map›Paper›PMID 37363174›Full record

ArticleFrontiers in psychiatry2023

Electroconvulsive therapy triggers a reversible decrease in brain N-acetylaspartate.

Vera J Erchinger, Alexander R Craven, Lars Ersland, Ketil J Oedegaard, Christoffer A Bartz-Johannessen, Åsa Hammar, Jan Haavik, Frank Riemer, Ute Kessler, Leif Oltedal

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Vera J ErchingerDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Alexander R CravenDepartment of Biological and Medical Psychology, University of Bergen, Bergen, Norway.
Lars ErslandDepartment of Clinical Engineering, Haukeland University Hospital, Bergen, Norway.
Ketil J OedegaardDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Christoffer A Bartz-JohannessenDivision of Psychiatry, Haukeland University Hospital, Bergen, Norway.
Åsa HammarDepartment of Biological and Medical Psychology, University of Bergen, Bergen, Norway.
Jan HaavikDivision of Psychiatry, Haukeland University Hospital, Bergen, Norway.
Frank RiemerMohn Medical Imaging and Visualization Centre, Department of Radiology, Haukeland University Hospital, Bergen, Norway.
Ute KesslerDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Leif OltedalDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Haukeland University Hospital · NOUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Based on previous research on electroconvulsive therapy (ECT) we have proposed a model where Methods: Using MR spectroscopy, we investigated 31 moderately to severely depressed patients and 19 healthy controls before, during, and after ECT or at similar time points (for controls). We tested whether biochemical alterations in tNAA, choline, mI, and Glx lend support to the Results: Levels of tNAA in the anterior cingulate cortex decreased after an ECT treatment series (average 10.6 sessions) by 6% ( Discussion: Our findings suggest that prior research must be interpreted with care, as several referencing and processing methods have been used in the past. Yet, the results for tNAA were robust across quantification methods and concur with relevant parts of the

Indexed as

1H-MRS nuclear magnetic resonance spectroscopycholinedepressionelectroconvulsive therapyglutamatemyoinositolneurometabolites

Identifiers

PMID37363174
PMCPMC10289547
OpenAlexW4380084891

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.