Evidence map›Paper›PMID 37365243›Full record

ArticleMolecular psychiatry2023

Activation of β

Ming Jin, Zhiyun Wei, Nagendran Ramalingam, Meng Xiao, Anqi Xu, Xiaohan Yu, Qingyang Song, Wen Liu, Jianhua Zhao, Dainan Zhang and 2 more

Abstract readNews
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. The Role of c-Abl in Alzheimer's Disease: Guilty or not Guilty?Cellular and molecular neurobiology · 2025
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Implication of Central βArchiv der Pharmazie · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Ming JinAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Zhiyun WeiAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Nagendran RamalingamAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.ORCID 0000-0002-9459-3593
Meng XiaoDepartment of Neurology, Xinxiang Medical University, Xinxiang, 453100, China.
Anqi XuDepartment of Neurology, Xinxiang Medical University, Xinxiang, 453100, China.
Xiaohan YuDepartment of Neurology, Xinxiang Medical University, Xinxiang, 453100, China.
Qingyang SongDepartment of Neurology, Xinxiang Medical University, Xinxiang, 453100, China.
Wen LiuAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Jianhua ZhaoDepartment of Neurology, Xinxiang Medical University, Xinxiang, 453100, China.
Dainan ZhangDepartment of Neurology, Xinxiang Medical University, Xinxiang, 453100, China.
Dennis J SelkoeAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.ORCID 0000-0001-8846-9767
Shaomin LiAnn Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA. sli11@bwh.harvard.edu.ORCID 0000-0001-9451-2151
Brigham and Women's Hospital · USXinxiang Medical University · CNBeijing University of Chinese Medicine · CNCapital Medical University · CNHenan Institute of Technology · CN

Funding

TRANSGENICS AND PRESENILIN FUNCTIONP01AG015379 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI BEREZOVSKA, OKSANA · 1998 to 2023
$51.3M
AGING IN THE BRAIN--ROLE OF THE FIBROUS PROTEINSR01AG006173 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SELKOE, DENNIS J · 1985 to 2016
$2.5M
NIA NIH HHS P01 AG015379U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R01AG006173
6 · The paper itself

Abstract

We previously reported that prolonged exposure to an enriched environment (EE) enhances hippocampal synaptic plasticity, with one of the significant mechanistic pathways being activation of β

Indexed as

Amyloid beta-PeptidesHippocampusAnimalsEpigenesis, GeneticMiceMice, KnockoutSignal TransductionAmyloid beta-Peptides

Identifiers

PMID37365243
OpenAlexW4382024715

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.