Evidence map›Paper›PMID 37366485›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2023

Retinal Microvascular Diameters are Associated with Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus.

Jing Feng, Xiaohua Xie, Zhenjie Teng, Wenjie Fei, Yunfeng Zhen, Jingzhen Liu, Liqun Yang, Shuchun Chen

Abstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing FengDepartment of Endocrinology, Hebei Medical University, Shijiazhuang, Hebei Province, People's Republic of China.
Xiaohua XieDepartment of Neurology, Hebei General Hospital, Shijiazhuang, Hebei Province, People's Republic of China.
Zhenjie TengDepartment of Neurology, Hebei General Hospital, Shijiazhuang, Hebei Province, People's Republic of China.
Wenjie FeiDepartment of Endocrinology, Hebei Medical University, Shijiazhuang, Hebei Province, People's Republic of China.
Yunfeng ZhenDepartment of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei Province, People's Republic of China.
Jingzhen LiuDepartment of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei Province, People's Republic of China.
Liqun YangDepartment of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei Province, People's Republic of China.
Shuchun ChenDepartment of Endocrinology, Hebei Medical University, Shijiazhuang, Hebei Province, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the association between retinal microvascular diameters and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM). Methods: A total of 690 patients with T2DM were included in this retrospective study. Patients were divided into DKD and non-DKD groups according to urine microalbumin/creatinine ratio and estimated glomerular filtration rate. Retinal microvascular diameters were measured by the automated retinal image analysis system. Multivariate logistic regression analysis and restricted cubic splines were used to assess the relationships between the retinal microvascular diameters and DKD in patients with T2DM. Results: Multivariate logistic regression showed that widened diameters of retinal venules and narrowed diameters of retinal arterioles were associated with DKD after adjusting for potential confounding variables. There was a significant linear trend between the diameters of superior temporal retinal venula ( Conclusion: Wider retinal venular diameters and narrower retinal arteriolar diameters were associated with an increased risk of DKD in patients with T2DM. Widened retinal venular diameters, especially CRVE, superior and inferior temporal retinal venula, were positively associated with an increased risk of DKD in a linear fashion. In contrast, narrowed retinal arteriolar diameters were associated with the risk of DKD in a non-linear fashion.

Indexed as

diabetic kidney diseasediameterretinal arteriolesretinal venulestype 2 diabetes mellitus

Identifiers

PMID37366485
PMCPMC10290843

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.