Evidence map›Paper›PMID 37370246›Full record

ArticleCancer biology & therapy2023

LncRNA ITGB2-AS1 promotes cisplatin resistance of non-small cell lung cancer by inhibiting ferroptosis via activating the FOSL2/NAMPT axis.

Huiyong Chen, Linhui Wang, Jingting Liu, Zihao Wan, Lin Zhou, Hongliang Liao, Renping Wan

Open access · goldAbstract read
In one paragraph

Article in Cancer biology & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Huiyong ChenDepartment of Thoracic Surgery, Yuebei People's Hospital, Shantou University, Shaoguan, Guangdong, People's Republic of China.
Linhui WangDepartment of Pathology, Yuebei People's Hospital, Shantou University, Shaoguan, Guangdong, People's Republic of China.
Jingting LiuDepartment of Thoracic Surgery, Yuebei People's Hospital, Shantou University, Shaoguan, Guangdong, People's Republic of China.
Zihao WanCollege of Physical Education and Health, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Lin ZhouDepartment of Thoracic Surgery, Yuebei People's Hospital, Shantou University, Shaoguan, Guangdong, People's Republic of China.
Hongliang LiaoDepartment of Thoracic Surgery, Yuebei People's Hospital, Shantou University, Shaoguan, Guangdong, People's Republic of China.
Renping WanDepartment of Thoracic Surgery, Yuebei People's Hospital, Shantou University, Shaoguan, Guangdong, People's Republic of China.ORCID 0000-0001-6246-7755
Shantou University · CNGuangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cisplatin resistance is a major therapeutic challenge in non-small cell lung cancer (NSCLC). Herein, the regulatory role of long non-coding RNA (lncRNA) ITGB2-AS1 in regulating NSCLC cisplatin resistance was investigated. NSCLC cisplatin resistance cells were constructed using A549 and H1975 cells. Cell viability and proliferation were detected by MTT assay and colony formation assay, respectively. Cell apoptosis and cell cycle were examined by flow cytometry. GSH, MDA, ROS, and Fe

Indexed as

Carcinoma, Non-Small-Cell LungFerroptosisLung NeoplasmsMicroRNAsRNA, Long NoncodingCell Line, TumorCell ProliferationCisplatinCytokinesFos-Related Antigen-2Gene Expression Regulation, NeoplasticHumansNicotinamide PhosphoribosyltransferaseTumor Suppressor Protein p53CisplatinCytokinesFOSL2 protein, humanFos-Related Antigen-2MicroRNAsNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humanRNA, Long NoncodingTumor Suppressor Protein p53cisplatin resistanceferroptosisLncRNA ITGB2-AS1NAMPTNon-small cell lung cancer

Identifiers

PMID37370246
PMCPMC10308868
OpenAlexW4382344776

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.