Evidence map›Paper›PMID 37371663›Full record

ArticleBiomedicines2023

Serum Asprosin Correlates with Indirect Insulin Resistance Indices.

Małgorzata Mirr, Anna Braszak-Cymerman, Aleksandra Ludziejewska, Matylda Kręgielska-Narożna, Paweł Bogdański, Wiesław Bryl, Maciej Owecki

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Małgorzata MirrDepartment of Public Health, Poznan University of Medical Sciences, Rokietnicka St. 4, 60-806 Poznań, Poland.
Anna Braszak-CymermanDepartment of Internal Diseases, Metabolic Disorders and Hypertension, Poznan University of Medical Sciences, Szamarzewskiego St. 84, 60-569 Poznań, Poland.ORCID 0000-0001-6992-8446
Aleksandra LudziejewskaDepartment of Laboratory Diagnostics, Poznan University of Medical Sciences, Szamarzewskiego St. 84, 60-569 Poznań, Poland.
Matylda Kręgielska-NarożnaDepartment of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznan University of Medical Sciences, Szamarzewskiego St. 84, 60-569 Poznań, Poland.
Paweł BogdańskiDepartment of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznan University of Medical Sciences, Szamarzewskiego St. 84, 60-569 Poznań, Poland.ORCID 0000-0002-0563-1624
Wiesław BrylDepartment of Internal Diseases, Metabolic Disorders and Hypertension, Poznan University of Medical Sciences, Szamarzewskiego St. 84, 60-569 Poznań, Poland.
Maciej OweckiDepartment of Public Health, Poznan University of Medical Sciences, Rokietnicka St. 4, 60-806 Poznań, Poland.ORCID 0000-0002-9060-0274
Poznan University of Medical Sciences · PL

Funding

Large research grant from statutory funding for young researchers - doctoral students of the Doctoral School of Poznań University of Medical Sciences for 2021 project number 4718
6 · The paper itself

Abstract

BACKGROUND AND

objectivesInsulin resistance is a major contributor to the development of type 2 diabetes and can be assessed using indirect indicators calculated from non-invasive tests. Asprosin is a recently discovered adipokine with a postulated effect on glycemic regulation. This study aimed to investigate the correlation between serum asprosin levels and insulin resistance indices. The correlation between circulating asprosin and obesity indices was also investigated. MATERIALS AND

methodsA total of 50 non-diabetic patients with obesity and 50 healthy volunteers were studied. Laboratory data, including circulating asprosin and anthropometric data, were collected. The following insulin resistance indices were calculated: triglyceride-glucose index (TyG), TyG-neck circumference (TyG-NC), TyG-neck circumference to height ratio (TyG-NHtR), TyG-waist circumference (TyG-WC), TyG-waist to height ratio (TyG-WHtR), TyG-body mass index (TyG-BMI), and the ratio between triglycerides and high-density cholesterol (TG/HDLc). The obtained data were analyzed separately for males and females.

resultsAsprosin concentrations were significantly higher in obese patients (

conclusionsAsprosin can be considered a marker of obesity and insulin resistance.

Indexed as

adipokineasprosininsulin resistanceobesity

Identifiers

PMID37371663
PMCPMC10295799
OpenAlexW4378619573

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.