Evidence map›Paper›PMID 37371750›Full record

ReviewBiomedicines2023

Human IGF2 Gene Epigenetic and Transcriptional Regulation: At the Core of Developmental Growth and Tumorigenic Behavior.

Pierluigi Scalia, Stephen J Williams, Yoko Fujita-Yamaguchi

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Insulin-Like Growth Factor 2 Reverses Synaptic and Cognitive Deficits in Fetal Growth Restriction Mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Pierluigi ScaliaISOPROG-Somatolink EPFP Research Network, Philadelphia, PA 19102, USA, and 93100 Caltanissetta, Italy.ORCID 0000-0002-5911-1640
Stephen J WilliamsISOPROG-Somatolink EPFP Research Network, Philadelphia, PA 19102, USA, and 93100 Caltanissetta, Italy.
Yoko Fujita-YamaguchiArthur Riggs Diabetes & Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Research Network (United States) · USCity of Hope · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulation of the human

Indexed as

BWS, Beckwith–Wiedemann syndromeCCD, centrally conserved domainCNV, copy number variationCTCF, CCCTC binding factorDMD, differentially methylated domainDMR, differentially methylated regionGOM, gain of methylationICR1, imprinting control region 1(IGF2/H19) IG-DMR, intergenic differentially methylated regionIGF2, insulin-like growth factor 2 geneIGF-II, insulin-like growth factor-2 peptideLOI, loss of imprintingLOM, loss of methylationMOI, maintenance of imprintingmRNA transcriptp0–p4: IGF2 promoters 0–4SRS, Silver Russel SyndromeTF: transcription factorUPD, uniparental disomyWT1, Wilms Tumor protein 1

Identifiers

PMID37371750
PMCPMC10296432
OpenAlexW4380047890

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.