Evidence map›Paper›PMID 37371978›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Biomarkers of Oxidative Stress in Healthy Infants within the First Three Days after Birth.

Mónica Cavia-Saiz, Juan Arnaez, Amaia Cilla, Laura Puente, Laura C Garcia-Miralles, Pilar Muñiz

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mónica Cavia-SaizDepartment of Biotechnology and Food Science, Faculty of Sciences, Universidad de Burgos, Plaza Misael Bañuelos, 09001 Burgos, Spain.
Juan ArnaezNeonatal Unit, Department of Pediatrics, University Hospital of Burgos, Islas Baleares s/n, 09006 Burgos, Spain.ORCID 0000-0001-8883-5181
Amaia CillaDepartment of Pediatrics, Hospital Universitario de Burgos, Islas Baleares s/n, 09006 Burgos, Spain.
Laura PuenteDepartment of Pediatrics, Hospital Universitario de Burgos, Islas Baleares s/n, 09006 Burgos, Spain.
Laura C Garcia-MirallesDepartment of Pediatrics, Hospital Universitario de Burgos, Islas Baleares s/n, 09006 Burgos, Spain.
Pilar MuñizDepartment of Biotechnology and Food Science, Faculty of Sciences, Universidad de Burgos, Plaza Misael Bañuelos, 09001 Burgos, Spain.ORCID 0000-0002-9306-0082

Funding

Fundación Burgos por la Investigación de la Salud 1088Gerencia Regional de Salud de Castilla y León GRS 1773/A/18
6 · The paper itself

Abstract

The clinical relevance of stress biomarkers in newborns is well established. Currently, oxidative stress (OS) parameters are seen to play an important role in neonatal resuscitation guidelines, and a link has been observed between the amount of oxygen delivered and the level of OS and the development of various pathologies. The aim of the current study was to investigate changes in neonatal plasma and urine OS status during the first hours after birth. A lower antioxidant capacity (TAC) and higher levels of malondialdehyde in blood were observed in newborns at the time of birth compared with results 48 h postnatally. The urine revealed a significant and progressive increase in TAC and creatinine during the first 36 h of life, with a progressive decline thereafter. Meanwhile, malondialdehyde in urine samples showed no significant differences over time. Overall, the correlation between blood and urine parameters was poor, except for the relationship between umbilical vein glutathione reduced/oxidized ratio and urine malondialdehyde (r = 0.7;

Indexed as

birthcarbonylcord bloodcreatinineglutathioneinfantmalondialdehydeoxidative stress

Identifiers

PMID37371978
PMCPMC10295668

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.