Evidence map›Paper›PMID 37374053›Full record

ReviewLife (Basel, Switzerland)2023

Is There Still a Place for Surgery in Patients with PCOS? A Review.

Luigi Della Corte, Dominga Boccia, Mario Palumbo, Antonio Mercorio, Carlo Ronsini, Giuseppe Bifulco, Pierluigi Giampaolino

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Combined Multiomics Analysis Reveals the Role ofReproductive medicine and biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Luigi Della CorteDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0002-0584-2181
Dominga BocciaDepartment of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.
Mario PalumboDepartment of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.
Antonio MercorioDepartment of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0002-2113-7706
Carlo RonsiniDepartment of Woman, Child and General and Specialized Surgery, School of Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-9023-282X
Giuseppe BifulcoDepartment of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.
Pierluigi GiampaolinoDepartment of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.
University of Naples Federico II · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe surgical management of polycystic ovary syndrome (PCOS) represents an unclear option compared to medical therapy, and it is necessary to deepen the role of minimally invasive surgery, represented by laparoscopic ovarian drilling (LOD) and transvaginal hydrolaparoscopy (THL), for the treatment of PCOS in infertile women resistant to drug therapy and to establish its success in terms of ovulation and pregnancy rates.

methodsA search was performed in the main electronic databases (MEDLINE, EMBASE, Web of Science, PubMed, and the Cochrane Library) from 1994 to October 2022 in order to evaluate the role of surgery in patients with PCOS resistant to pharmacological treatment. Only original scientific articles in English were included.

resultsSeventeen studies were analyzed in this review. In all analyzed studies, more than 50% of the population underwent spontaneous ovulation after surgical treatment without great differences between the two surgical techniques (LOD and THL). More than 40% of patients delivered, with a higher rate after LOD, although eight ectopic pregnancies and sixty-three miscarriages were reported. A lower risk of adhesion formation after THL has been reported. No clear data regarding the effect of surgery on the regularization of the menstrual cycle has been described. A reduction in LH and AMH serum levels as well as the LH/FSH ratio compared to preoperative levels for both surgical techniques has been described.

conclusionsDespite the scarcity and heterogeneity of data, surgical therapy could be considered an effective and safe approach in the management of PCOS patients with resistance to pharmacological treatment who desire to become pregnant.

Indexed as

clomiphene citrategonadotrophinslaparoscopic ovarian drillingpolycystic ovarian syndrometransvaginal hydrolaparoscopy

Identifiers

PMID37374053
PMCPMC10304625
OpenAlexW4378619150

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.