Evidence map›Paper›PMID 37375567›Full record

Trial reportNutrients2023

Effects of Oral Cannabidiol on Health and Fitness in Healthy Adults: An 8-Week Randomized Trial.

Victoria A Flores, Jacob N Kisiolek, Arjun Ramani, Ryland Townsend, Edwin Rodriguez, Blake Butler, Laura K Stewart

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Victoria A FloresDepartment of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO 80639, USA.ORCID 0000-0002-2686-4603
Jacob N KisiolekDepartment of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO 80639, USA.
Arjun RamaniDepartment of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO 80639, USA.
Ryland TownsendDepartment of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO 80639, USA.
Edwin RodriguezDepartment of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO 80639, USA.
Blake ButlerDepartment of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO 80639, USA.
Laura K StewartDepartment of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO 80639, USA.

Funding

University of Northern Colorado None Available
6 · The paper itself

Abstract

backgroundThere is a lack of research on the effects of cannabidiol (CBD) on health-related fitness, physical activity, cognitive health, psychological wellbeing, and concentrations of C-reactive protein (CRP) in healthy individuals. CBD has potential anti-inflammatory and neuroprotective effects.

methodsThis study aimed to investigate the effects of 8 weeks of CBD on the above-mentioned measures in healthy individuals. Forty-eight participants were randomized into two groups receiving either oral capsules of 50 mg of CBD or a calorie-matched placebo daily. Participants completed pre- and post-intervention assessments, including blood draws, body composition, fitness, physical activity, and self-reported surveys.

resultsThere were no significant differences between groups regarding body composition, aerobic fitness, muscular strength, physical activity, cognitive health, psychological wellbeing, and resting CRP concentrations. However, the placebo group experienced a decline in mean peak power and relative peak power compared to the CBD group.

conclusionsThe results suggest that 8 weeks of CBD supplementation may prevent declines in anaerobic fitness over time. However, long-term CBD supplementation may not be beneficial for altering measures of health-related fitness, mental health, and inflammation in healthy individuals.

Indexed as

CannabidiolAdultDouble-Blind MethodHealth StatusHumansInflammationCannabidiolcannabinoidscognitionhealthy adultsphysical performancepsychological wellbeing

Identifiers

PMID37375567
PMCPMC10301202

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.