Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
21 authors at 5 institutions in 2 countries.
Maíra Bernardes AlvesNúcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília (UnB), Brasília 70910-900, Brazil.
Andreanne Gomes VasconcelosNúcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília (UnB), Brasília 70910-900, Brazil.ORCID 0000-0002-9651-1598
Amandda Évelin Silva de CarvalhoLaboratório de Hematologia e Células-Tronco (LHCT), Faculdade de Ciências da Saúde, Universidade de Brasília (UnB), Brasília 70910-900, Brazil.
Bruno Silva SáNúcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília (UnB), Brasília 70910-900, Brazil.ORCID 0000-0002-3644-4792
Maria Júlia Lima GonçalvesDepartment of Biomedicine, Centro Universitário do Distrito Federal (UDF), Brasília 70390-045, Brazil.
Liz Nayara Ribeiro da Costa Lima MouraDepartment of Biomedicine, Centro Universitário do Distrito Federal (UDF), Brasília 70390-045, Brazil.
Ana Karolinne da Silva BritoDepartamento de Biofísica e Fisiologia, Centro de Ciências da Saúde (DBFis/CCS), Universidade Federal do Piauí (UFPI), Teresina 64049-550, Brazil.ORCID 0000-0002-9575-2103
José Vinícius de Sousa FrançaDepartamento de Biofísica e Fisiologia, Centro de Ciências da Saúde (DBFis/CCS), Universidade Federal do Piauí (UFPI), Teresina 64049-550, Brazil.ORCID 0000-0001-5716-811X
Maria do Carmo de Carvalho E MartinsDepartamento de Biofísica e Fisiologia, Centro de Ciências da Saúde (DBFis/CCS), Universidade Federal do Piauí (UFPI), Teresina 64049-550, Brazil.ORCID 0000-0002-9107-2485
Márcia Dos Santos RizzoInterdisciplinary Laboratory for Advanced Materials (LIMAV), Department of Morphology, Health Sciences Center (DMOR/CCS), Federal University of Piauí (UFPI), Teresina 64049-550, Brazil.ORCID 0000-0003-4276-3113
Susana SoaresCESAM-Centre for Environmental and Marine Studies, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal.
Verónica BastosCESAM-Centre for Environmental and Marine Studies, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-9882-4766
Felipe Saldanha de AraujoPeople & Science Pesquisa Desenvolvimento e Inovação LTDA, Brasília 70790-120, Brazil.
Bassam Felipe MogharbelInstituto de Pesquisa Pelé Pequeno Príncipe, Curitiba 80240-020, Brazil.ORCID 0000-0002-1338-0693
Katherine Athayde Teixeira de CarvalhoInstituto de Pesquisa Pelé Pequeno Príncipe, Curitiba 80240-020, Brazil.ORCID 0000-0003-4860-2855
Helena OliveiraCESAM-Centre for Environmental and Marine Studies, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4673-0696
Alexandra PlácidoDepartamento de Bioquímica, Faculdade de Ciências (FCUP), Universidade do Porto (UP), 4169-007 Porto, Portugal.
Daniel Dias Rufino ArcanjoDepartamento de Biofísica e Fisiologia, Centro de Ciências da Saúde (DBFis/CCS), Universidade Federal do Piauí (UFPI), Teresina 64049-550, Brazil.ORCID 0000-0001-7021-2744
Eder Alves BarbosaNúcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília (UnB), Brasília 70910-900, Brazil.ORCID 0000-0002-7613-4414
José Roberto de Souza de Almeida LeiteNúcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília (UnB), Brasília 70910-900, Brazil.ORCID 0000-0002-1096-3236
Universidade de Brasília · BRUniversidade Federal do Piauí · BRUniversity of Aveiro · PTCentro Universitário do Distrito Federal · BRUniversidade do Porto · PT
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Lycopene is a carotenoid with potential use in the treatment of chronic illnesses. Here, different formulations of lycopene were studied: lycopene-rich extract from red guava (LEG), purified lycopene from red guava (LPG) and a self-emulsifying drug delivery system loaded with LPG (nanoLPG). The effects of administering orally various doses of LEG to hypercholesterolemic hamsters were evaluated regarding the liver function of the animals. The cytotoxicity of LPG in Vero cells was analyzed by a crystal violet assay and by fluorescence microscopy. In addition, nanoLPG was employed in stability tests. LPG and nanoLPG were tested for their cytotoxic effect on human keratinocytes and antioxidant capacity on cells in an endothelial dysfunction model in an isolated rat aorta. Finally, the effect of different nanoLPG concentrations on the expression of immune-related genes (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Lycopene from Red Guava ( · full record | Socratic